Menopausal hormone therapy: examining cardiovascular and clinical impacts of treatment

Christine L. Chiu, Joanne M. Lind*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


Postmenopausal women have reduced levels of female sex hormones and this may play a significant role in the onset of cardiovascular disease. Menopausal hormone therapy (MHT), which is primarily prescribed for the treatment of perimenopausal symptoms, has been associated with risk of coronary heart disease, hypertension and stroke in women. This review will summarize the outcomes of observational studies and randomized clinical trials that have investigated the influence of MHT use on the cardiovascular system. In addition, it will explore how the timing of MHT prescription relative to menopause, dosage and route of administration may alter the impact of MHT on cardiovascular health.

Original languageEnglish
Pages (from-to)427-435
Number of pages9
JournalFuture Cardiology
Issue number3
Publication statusPublished - May 2013
Externally publishedYes


  • blood pressure
  • cardiovascular disease
  • coronary artery disease
  • estrogen
  • hypertension
  • menopausal hormone therapy
  • menopause
  • stroke


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