Metabolite profiling reveals predictive biomarkers and the absence of β-methyl amino-l-alanine in plasma from individuals diagnosed with amyotrophic lateral sclerosis

Chemistry

• Amount 16%
• Biological Marker 71%
• Capillary Zone Electrophoresis 45%
• Classifier 54%
• Creatine 100%
• Creatinine 95%
• High Resolution Mass Spectrometry (HRMS) 43%
• Marker 34%
• Metabolite 56%
• Neurotoxic 50%
• Plasma 49%

Medicine & Life Sciences

• Alanine 80%
• Amyotrophic Lateral Sclerosis 85%
• Amyotrophic lateral sclerosis 1 21%
• Amyotrophic Lateral Sclerosis 10 28%
• Area Under Curve 25%
• Biomarkers 51%
• Capillary Electrophoresis 20%
• Creatine 37%
• Creatinine 25%
• Discriminant Analysis 17%
• Disease Progression 12%
• Essential Amino Acids 20%
• Isotopes 17%
• Mass Spectrometry 14%
• Metabolome 17%
• Methylhistidines 29%
• Proteins 5%
• ROC Curve 13%
• Support Vector Machine 19%