Metal-enhanced fluorescence in the life sciences

Here, now and beyond

Wei Deng, Fang Xie, Henrique T. M. C. M. Baltar, Ewa M. Goldys*

*Corresponding author for this work

Research output: Contribution to journalReview article

81 Citations (Scopus)

Abstract

We discuss the phenomenon of enhanced fluorescence in the proximity of metal nanostructures addressing the question of how much fluorescence signal can be obtained from fluorophores in such altered environments. We review its applicability for the methodologies used in the life science, such as immunoassays, flow cytometry and bioimaging. Experimental and theoretical scenarios employing various metal nanostructures-such as homogeneous enhancing substrates, fluorescence-enhancing microbeads, and metal core-dielectric shell nanocomposites-are described.

Original languageEnglish
Pages (from-to)15695-15708
Number of pages14
JournalPhysical Chemistry Chemical Physics
Volume15
Issue number38
DOIs
Publication statusPublished - 14 Oct 2013

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