TY - JOUR
T1 - Metal-enhanced fluorescence in the life sciences
T2 - Here, now and beyond
AU - Deng, Wei
AU - Xie, Fang
AU - Baltar, Henrique T. M. C. M.
AU - Goldys, Ewa M.
PY - 2013/10/14
Y1 - 2013/10/14
N2 - We discuss the phenomenon of enhanced fluorescence in the proximity of metal nanostructures addressing the question of how much fluorescence signal can be obtained from fluorophores in such altered environments. We review its applicability for the methodologies used in the life science, such as immunoassays, flow cytometry and bioimaging. Experimental and theoretical scenarios employing various metal nanostructures-such as homogeneous enhancing substrates, fluorescence-enhancing microbeads, and metal core-dielectric shell nanocomposites-are described.
AB - We discuss the phenomenon of enhanced fluorescence in the proximity of metal nanostructures addressing the question of how much fluorescence signal can be obtained from fluorophores in such altered environments. We review its applicability for the methodologies used in the life science, such as immunoassays, flow cytometry and bioimaging. Experimental and theoretical scenarios employing various metal nanostructures-such as homogeneous enhancing substrates, fluorescence-enhancing microbeads, and metal core-dielectric shell nanocomposites-are described.
UR - http://www.scopus.com/inward/record.url?scp=84884162509&partnerID=8YFLogxK
U2 - 10.1039/c3cp50206f
DO - 10.1039/c3cp50206f
M3 - Review article
C2 - 23552881
AN - SCOPUS:84884162509
VL - 15
SP - 15695
EP - 15708
JO - Physical Chemistry Chemical Physics
JF - Physical Chemistry Chemical Physics
SN - 1463-9076
IS - 38
ER -