Metal-enhanced fluorescence in the life sciences: Here, now and beyond

Wei Deng, Fang Xie, Henrique T. M. C. M. Baltar, Ewa M. Goldys

Research output: Contribution to journalReview articleResearchpeer-review

Abstract

We discuss the phenomenon of enhanced fluorescence in the proximity of metal nanostructures addressing the question of how much fluorescence signal can be obtained from fluorophores in such altered environments. We review its applicability for the methodologies used in the life science, such as immunoassays, flow cytometry and bioimaging. Experimental and theoretical scenarios employing various metal nanostructures-such as homogeneous enhancing substrates, fluorescence-enhancing microbeads, and metal core-dielectric shell nanocomposites-are described.

LanguageEnglish
Pages15695-15708
Number of pages14
JournalPhysical Chemistry Chemical Physics
Volume15
Issue number38
DOIs
Publication statusPublished - 14 Oct 2013

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life sciences
Metals
Fluorescence
fluorescence
Nanostructures
metals
immunoassay
cytometry
Flow cytometry
Fluorophores
proximity
Nanocomposites
nanocomposites
methodology
Substrates

Cite this

Deng, Wei ; Xie, Fang ; Baltar, Henrique T. M. C. M. ; Goldys, Ewa M. / Metal-enhanced fluorescence in the life sciences : Here, now and beyond. In: Physical Chemistry Chemical Physics. 2013 ; Vol. 15, No. 38. pp. 15695-15708.
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Metal-enhanced fluorescence in the life sciences : Here, now and beyond. / Deng, Wei; Xie, Fang; Baltar, Henrique T. M. C. M.; Goldys, Ewa M.

In: Physical Chemistry Chemical Physics, Vol. 15, No. 38, 14.10.2013, p. 15695-15708.

Research output: Contribution to journalReview articleResearchpeer-review

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