Metal-enhanced fluorescence in the life sciences: Here, now and beyond

Wei Deng; Fang Xie; Henrique T. M. C. M. Baltar; Ewa M. Goldys

doi:10.1039/c3cp50206f

Metal-enhanced fluorescence in the life sciences: Here, now and beyond

Wei Deng, Fang Xie, Henrique T. M. C. M. Baltar, Ewa M. Goldys^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

136 Citations (Scopus)

Abstract

We discuss the phenomenon of enhanced fluorescence in the proximity of metal nanostructures addressing the question of how much fluorescence signal can be obtained from fluorophores in such altered environments. We review its applicability for the methodologies used in the life science, such as immunoassays, flow cytometry and bioimaging. Experimental and theoretical scenarios employing various metal nanostructures-such as homogeneous enhancing substrates, fluorescence-enhancing microbeads, and metal core-dielectric shell nanocomposites-are described.

Original language	English
Pages (from-to)	15695-15708
Number of pages	14
Journal	Physical Chemistry Chemical Physics
Volume	15
Issue number	38
DOIs	https://doi.org/10.1039/c3cp50206f
Publication status	Published - 14 Oct 2013

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title = "Metal-enhanced fluorescence in the life sciences: Here, now and beyond",

abstract = "We discuss the phenomenon of enhanced fluorescence in the proximity of metal nanostructures addressing the question of how much fluorescence signal can be obtained from fluorophores in such altered environments. We review its applicability for the methodologies used in the life science, such as immunoassays, flow cytometry and bioimaging. Experimental and theoretical scenarios employing various metal nanostructures-such as homogeneous enhancing substrates, fluorescence-enhancing microbeads, and metal core-dielectric shell nanocomposites-are described.",

author = "Wei Deng and Fang Xie and Baltar, \{Henrique T. M. C. M.\} and Goldys, \{Ewa M.\}",

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T2 - Here, now and beyond

AU - Deng, Wei

AU - Xie, Fang

AU - Baltar, Henrique T. M. C. M.

AU - Goldys, Ewa M.

PY - 2013/10/14

Y1 - 2013/10/14

N2 - We discuss the phenomenon of enhanced fluorescence in the proximity of metal nanostructures addressing the question of how much fluorescence signal can be obtained from fluorophores in such altered environments. We review its applicability for the methodologies used in the life science, such as immunoassays, flow cytometry and bioimaging. Experimental and theoretical scenarios employing various metal nanostructures-such as homogeneous enhancing substrates, fluorescence-enhancing microbeads, and metal core-dielectric shell nanocomposites-are described.

AB - We discuss the phenomenon of enhanced fluorescence in the proximity of metal nanostructures addressing the question of how much fluorescence signal can be obtained from fluorophores in such altered environments. We review its applicability for the methodologies used in the life science, such as immunoassays, flow cytometry and bioimaging. Experimental and theoretical scenarios employing various metal nanostructures-such as homogeneous enhancing substrates, fluorescence-enhancing microbeads, and metal core-dielectric shell nanocomposites-are described.

UR - https://www.scopus.com/pages/publications/84884162509

U2 - 10.1039/c3cp50206f

DO - 10.1039/c3cp50206f

M3 - Review article

C2 - 23552881

AN - SCOPUS:84884162509

SN - 1463-9076

VL - 15

SP - 15695

EP - 15708

JO - Physical Chemistry Chemical Physics

JF - Physical Chemistry Chemical Physics

IS - 38

ER -

Metal-enhanced fluorescence in the life sciences: Here, now and beyond

Abstract

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