Metal reactivity: its influence on primary and revision outcomes

George Grammatopoulos, Hemant Pandit, Adrian Low, David Murray*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)


Outcome following Metal-on-Metal (MoM) Hip arthroplasty is dependent on patient, surgical and implant factors. This chapter describes the influence of metal reactivity on primary and revision outcome following MoM Hip arthroplasty. In doing so, we provide the evidence on metal reactivity on genetic and cellular/histology level and define the outcome of primary and revisions arthroplasties as reported by national registries, designer series and independent centres. Furthermore, this chapter highlights possible ways of improving outcome and describes the clinical pathways of patient management following MoM arthroplasty, described by national and international governing bodies.

Original languageEnglish
Title of host publicationMetal-on-metal bearings
Subtitle of host publicationa clinical practicum
EditorsLynne C. Jones, Warren O. Haggard, A. Seth Greenwald
Place of PublicationNew York
PublisherSpringer, Springer Nature
Number of pages24
ISBN (Electronic)9781461489993
ISBN (Print)9781461489986
Publication statusPublished - 1 Nov 2013
Externally publishedYes


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