Methodological recommendations for menstrual cycle research in sports and exercise

Xanne Janse de Jonge, Belinda Thompson, Ahreum Han

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Introduction: The aim of this review is to provide methodological recommendations for menstrual cycle research in exercise science and sports medicine based on a review of recent literature. Research in this area is growing, but often reports conflicting results and it is proposed that some of this may be explained by methodological issues. 

Methods: This review examined the menstrual cycle verification methodologies used in recent literature on exercise performance over the menstrual cycle identified through a literature search of PubMed and SportDiscus from 2008 until 2018. 

Results: Potential changes over the menstrual cycle are likely related to hormone fluctuations, however, only 44% of the selected studies measured the actual concentrations of the female steroid hormones estrogen and progesterone. It was shown that the likely inclusion of participants with anovulatory or luteal phase deficient cycles in combination with small participant numbers has impacted results in recent menstrual cycle research and consequently our understanding of this area. 

Conclusion: To improve the quality of future menstrual cycle research it is recommended that a combination of three methods is used to verify menstrual cycle phase: the calendar-based counting method combined with urinary luteinizing hormone surge testing and the measurement of serum estrogen and progesterone concentrations at the time of testing. A strict luteal phase verification limit of >16 nmol·L for progesterone should be set. It is also recommended that future research focusses on the inclusion of the late follicular estrogen peak. It is envisaged that these methodological recommendations will assist in clarifying some of the disagreement around the effects of the menstrual cycle on exercise performance and other aspects of exercise science and sports medicine.

LanguageEnglish
Pages2610-2617
Number of pages8
JournalMedicine and Science in Sports and Exercise
Volume51
Issue number12
DOIs
Publication statusPublished - Dec 2019
Externally publishedYes

Fingerprint

Menstrual Cycle
Sports
Research
Progesterone
Sports Medicine
Estrogens
Luteal Phase
Hormones
Luteinizing Hormone
PubMed
Steroids
Serum

Keywords

  • estrogen
  • progesterone
  • hormonal verification
  • review
  • performance

Cite this

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abstract = "Introduction: The aim of this review is to provide methodological recommendations for menstrual cycle research in exercise science and sports medicine based on a review of recent literature. Research in this area is growing, but often reports conflicting results and it is proposed that some of this may be explained by methodological issues. Methods: This review examined the menstrual cycle verification methodologies used in recent literature on exercise performance over the menstrual cycle identified through a literature search of PubMed and SportDiscus from 2008 until 2018. Results: Potential changes over the menstrual cycle are likely related to hormone fluctuations, however, only 44{\%} of the selected studies measured the actual concentrations of the female steroid hormones estrogen and progesterone. It was shown that the likely inclusion of participants with anovulatory or luteal phase deficient cycles in combination with small participant numbers has impacted results in recent menstrual cycle research and consequently our understanding of this area. Conclusion: To improve the quality of future menstrual cycle research it is recommended that a combination of three methods is used to verify menstrual cycle phase: the calendar-based counting method combined with urinary luteinizing hormone surge testing and the measurement of serum estrogen and progesterone concentrations at the time of testing. A strict luteal phase verification limit of >16 nmol·L for progesterone should be set. It is also recommended that future research focusses on the inclusion of the late follicular estrogen peak. It is envisaged that these methodological recommendations will assist in clarifying some of the disagreement around the effects of the menstrual cycle on exercise performance and other aspects of exercise science and sports medicine.",
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Methodological recommendations for menstrual cycle research in sports and exercise. / de Jonge, Xanne Janse; Thompson, Belinda; Han, Ahreum.

In: Medicine and Science in Sports and Exercise, Vol. 51, No. 12, 12.2019, p. 2610-2617.

Research output: Contribution to journalArticleResearchpeer-review

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