Methotrexate-induced optic neuropathy

Chandra Balachandran; Peter J. McCluskey; G. David Champion; G. Michael Halmagyi

Methotrexate-induced optic neuropathy

Chandra Balachandran, Peter J. McCluskey, G. David Champion, G. Michael Halmagyi

Research output: Contribution to journal › Article › peer-review

Abstract

A 53-year-old Caucasian woman with long-standing, well controlled, severe rheumatoid arthritis, treated with methotrexate, salazopyrin, naprosyn, prednisone and plaquenil, presented with progressive visual loss in each eye. She had a past history of non-necrotizing anterior scleritis that was treated with increased doses of prednisone. She developed left then right central scotomas, reduced vision and optic atrophy. Eventually a diagnosis of methotrexate-induced optic atrophy was made.

Original language	English
Pages (from-to)	440-441
Number of pages	2
Journal	Clinical and Experimental Ophthalmology
Volume	30
Issue number	6
Publication status	Published - Dec 2002
Externally published	Yes

Keywords

methotrexate
optic neuropathy
rheumatoid arthritis
side-effect

Cite this

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title = "Methotrexate-induced optic neuropathy",

abstract = "A 53-year-old Caucasian woman with long-standing, well controlled, severe rheumatoid arthritis, treated with methotrexate, salazopyrin, naprosyn, prednisone and plaquenil, presented with progressive visual loss in each eye. She had a past history of non-necrotizing anterior scleritis that was treated with increased doses of prednisone. She developed left then right central scotomas, reduced vision and optic atrophy. Eventually a diagnosis of methotrexate-induced optic atrophy was made.",

keywords = "methotrexate, optic neuropathy, rheumatoid arthritis, side-effect",

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year = "2002",

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AU - Balachandran, Chandra

AU - McCluskey, Peter J.

AU - Champion, G. David

AU - Halmagyi, G. Michael

PY - 2002/12

Y1 - 2002/12

N2 - A 53-year-old Caucasian woman with long-standing, well controlled, severe rheumatoid arthritis, treated with methotrexate, salazopyrin, naprosyn, prednisone and plaquenil, presented with progressive visual loss in each eye. She had a past history of non-necrotizing anterior scleritis that was treated with increased doses of prednisone. She developed left then right central scotomas, reduced vision and optic atrophy. Eventually a diagnosis of methotrexate-induced optic atrophy was made.

AB - A 53-year-old Caucasian woman with long-standing, well controlled, severe rheumatoid arthritis, treated with methotrexate, salazopyrin, naprosyn, prednisone and plaquenil, presented with progressive visual loss in each eye. She had a past history of non-necrotizing anterior scleritis that was treated with increased doses of prednisone. She developed left then right central scotomas, reduced vision and optic atrophy. Eventually a diagnosis of methotrexate-induced optic atrophy was made.

KW - methotrexate

KW - optic neuropathy

KW - rheumatoid arthritis

KW - side-effect

M3 - Article

C2 - 12427239

VL - 30

SP - 440

EP - 441

JO - Clinical and Experimental Ophthalmology

JF - Clinical and Experimental Ophthalmology

SN - 1442-6404

IS - 6

ER -

Methotrexate-induced optic neuropathy

Abstract

Keywords

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