MHC diversity and female age underpin reproductive success in an Australian icon; the Tasmanian Devil

Tracey Russell, Simeon Lisovski, Mats Olsson, Gregory Brown, Rebecca Spindler, Amanda Lane, Tamara Keeley, Chris Hibbard, Carolyn J. Hogg, Frédéric Thomas, Katherine Belov, Beata Ujvari, Thomas Madsen

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Devil Facial Tumour Disease (DFTD), a highly contagious cancer, has decimated Tasmanian devil (Sarcophilus harrisii) numbers in the wild. To ensure its long-term survival, a captive breeding program was implemented but has not been as successful as envisaged at its launch in 2005. We therefore investigated the reproductive success of 65 captive devil pair combinations, of which 35 produced offspring (successful pairs) whereas the remaining 30 pairs, despite being observed mating, produced no offspring (unsuccessful pairs). The devils were screened at six MHC Class I-linked microsatellite loci. Our analyses revealed that younger females had a higher probability of being successful than older females. In the successful pairs we also observed a higher difference in total number of heterozygous loci, i.e. when one devil had a high total number of heterozygous loci, its partner had low numbers. Our results therefore suggest that devil reproductive success is subject to disruptive MHC selection, which to our knowledge has never been recorded in any vertebrate. In order to enhance the success of the captive breeding program the results from the present study show the importance of using young (2-year old) females as well as subjecting the devils to MHC genotyping.

Original languageEnglish
Article number4175
Number of pages8
JournalScientific Reports
Volume8
Issue number1
DOIs
Publication statusPublished - 8 Mar 2018
Externally publishedYes

Bibliographical note

Copyright the Author(s) 2018. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Fingerprint Dive into the research topics of 'MHC diversity and female age underpin reproductive success in an Australian icon; the Tasmanian Devil'. Together they form a unique fingerprint.

Cite this