Microbial solute transporters

K. A. Hassan, I. T. Paulsen, L. D. H. Elbourne, Q. Ren, A. D. Cameron, P. J. F. Henderson

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    The era of structural biology and genomics has opened new horizons in our understanding of complex biological questions. The three-dimensional transporter structures have provided us invaluable information on the mechanisms of transporter function, while the comparative genomic approaches for the analysis of membrane transport systems rendered insights on how microbes adapt to their environment. The observations that organisms with similar lifestyles and/or ecologic niches display similar transporter profiles despite their phylogenetic differences strongly suggest the influence of the ambient environment on an organism's complement of membrane transport genes.
    Original languageEnglish
    Title of host publicationReference module in biomedical research
    EditorsMichael J Caplan
    Place of PublicationAmsterdam
    PublisherElsevier
    ISBN (Print)9780128012383
    DOIs
    Publication statusPublished - 2014

    Bibliographical note

    Previously published in The Desk encyclopedia of microbiology, Schaechter, Moselio (Ed) (2nd ed.), pp. 1121-1136 (2009)

    Keywords

    • Archaea
    • Eubacterial
    • Genome
    • Phylogenetic profiling
    • Protein family
    • Solute transporter

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