Microbiome changes in humans with Parkinson’s disease after photobiomodulation therapy: a retrospective study

Brian Bicknell; Ann Liebert; Craig S. McLachlan; Hosen Kiat

doi:10.3390/jpm12010049

Microbiome changes in humans with Parkinson’s disease after photobiomodulation therapy: a retrospective study

Brian Bicknell^*, Ann Liebert, Craig S. McLachlan, Hosen Kiat

^*Corresponding author for this work

Macquarie Medical School

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

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Abstract

There is a paucity of information on the effect of photobiomodulation therapy on gut micro-biome composition. Parkinson’s disease is a progressive neurological disorder with few management options, although the gut microbiome has been suggested as a potential avenue of treatment. We retrospectively analysed the microbiome from human stool samples from a previously published study, which had demonstrated the efficacy of photobiomodulation to treat Parkinson’s patients’ symptoms. Specifically, we have observed changes in the microbiome of Parkinson’s patients after a 12-week treatment regimen with photobiomodulation to the abdomen, neck, head and nose. Noted were positive changes in the Firmicutes to Bacteroidetes (F:B) ratio, which is often interpreted as a proxy for gut health.

Original language	English
Article number	49
Pages (from-to)	1-15
Number of pages	15
Journal	Journal of Personalized Medicine
Volume	12
Issue number	1
DOIs	https://doi.org/10.3390/jpm12010049
Publication status	Published - 5 Jan 2022

Bibliographical note

Copyright the Author(s) 2022. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.

Keywords

Microbiome
Parkinson’s disease
Photobiomodulation

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10.3390/jpm12010049Licence: CC BY

Publisher version (open access)Final published version, 3.69 MBLicence: CC BY

Cite this

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abstract = "There is a paucity of information on the effect of photobiomodulation therapy on gut micro-biome composition. Parkinson{\textquoteright}s disease is a progressive neurological disorder with few management options, although the gut microbiome has been suggested as a potential avenue of treatment. We retrospectively analysed the microbiome from human stool samples from a previously published study, which had demonstrated the efficacy of photobiomodulation to treat Parkinson{\textquoteright}s patients{\textquoteright} symptoms. Specifically, we have observed changes in the microbiome of Parkinson{\textquoteright}s patients after a 12-week treatment regimen with photobiomodulation to the abdomen, neck, head and nose. Noted were positive changes in the Firmicutes to Bacteroidetes (F:B) ratio, which is often interpreted as a proxy for gut health.",

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Microbiome changes in humans with Parkinson’s disease after photobiomodulation therapy: a retrospective study

Abstract

Bibliographical note

Keywords

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