Abstract
In this study, a microfluidic device, fabricated in PDMS. with an integrated sheathless electrospray emitter tip is described. A sample pre-treatment function was also added into the device, allowing neuropeptides in Ringer's salt solution to be desalted prior to mass spectrometry analyzation. The device was fabricated casting two PDMS substrates from a SU-8 master and subsequently irreversibly bonding them together using corona discharge treatment. The device showed excellent durability and the peptide sample could be analyzed without any traces of salts.
Original language | English |
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Title of host publication | Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
Publisher | Transducer Research Foundation |
Pages | 1501-1503 |
Number of pages | 3 |
Volume | 1 |
ISBN (Print) | 0974361119, 9780974361116 |
Publication status | Published - 2005 |
Event | 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 - Boston, MA, United States Duration: 9 Oct 2005 → 13 Oct 2005 |
Other
Other | 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 |
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Country/Territory | United States |
City | Boston, MA |
Period | 9/10/05 → 13/10/05 |
Keywords
- Electrospray ionization
- Mass spectrometry
- PDMS
- Sample desalting