Microfluidic high gradient magnetic cell separation

David W. Inglis*, Robert Riehn, James C. Sturm, Robert H. Austin

*Corresponding author for this work

Research output: Contribution to journalArticle

98 Citations (Scopus)
10 Downloads (Pure)

Abstract

Separation of blood cells by native susceptibility and by the selective attachment of magnetic beads has recently been demonstrated on microfluidic devices. We discuss the basic principles of how forces are generated via the magnetic susceptibility of an object and how microfluidics can be combined with micron-scale magnetic field gradients to greatly enhance in principle the fractionating power of magnetic fields. We discuss our efforts and those of others to build practical microfluidic devices for the magnetic separation of blood cells. We also discuss our attempts to integrate magnetic separation with other microfluidic features for developing handheld medical diagnostic tools.

Original languageEnglish
Article number08K101
Pages (from-to)1-3
Number of pages3
JournalJournal of Applied Physics
Volume99
Issue number8
DOIs
Publication statusPublished - 2006
Externally publishedYes

Bibliographical note

Copyright (2006) American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Journal of Applied Physics, 99:8, 08K101 (2006) and may be found at http://dx.doi.org/10.1063/1.2165782.

Fingerprint Dive into the research topics of 'Microfluidic high gradient magnetic cell separation'. Together they form a unique fingerprint.

Cite this