Mid-infrared fiber sources for real-time biomedical sensing

R. I. Woodward, M. R. Majewski, G. Bharathan, D. D. Hudson, A. Fuerbach, S. D. Jackson

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contribution

Abstract

The development of new, compact mid-infrared light sources is critical to enable biomedical sensing applications in resource-limited environments. Here, we review progress in fiber-based mid-IR sources, which are ideally suited for clinical environments due to their compact size and waveguide format. We first discuss recent developments in mid-IR supercontinuum sources, which exploit nonlinear optic phenomena in highly nonlinear materials (pumped by ultrashort pulse lasers) to generate broadband spectra. An emerging alternative approach is then presented, based on broadly tunable mid-IR fiber lasers, using the promising dysprosium ion to achieve orders of magnitude higher spectral power density than typical supercontinua. By employing an acousto-optic tunable filter for wavelength tuning, an electronically controlled swept-wavelength mid-IR fiber laser is developed, which is applied for absorption spectroscopy of ammonia (NH3)|an important biomarker|with 0.3 nm resolution and 40 ms acquisition time.

Original languageEnglish
Title of host publicationOptical Biopsy XVII
Subtitle of host publicationToward Real-Time Spectroscopic Imaging and Diagnosis
EditorsRobert R. Alfano, Stavros G. Demos, Angela B. Seddon
Place of PublicationPiscataway, NJ
PublisherSPIE
Pages1-8
Number of pages8
ISBN (Electronic)9781510623897
ISBN (Print)9781510623880
DOIs
Publication statusPublished - 2019
EventOptical Biopsy XVII: Toward Real-Time Spectroscopic Imaging and Diagnosis 2019 - San Francisco, United States
Duration: 5 Feb 20196 Feb 2019

Publication series

NameProceedings of SPIE
PublisherSPIE
Volume10873
ISSN (Print)1605-7422
ISSN (Electronic)2410-9045

Conference

ConferenceOptical Biopsy XVII: Toward Real-Time Spectroscopic Imaging and Diagnosis 2019
CountryUnited States
CitySan Francisco
Period5/02/196/02/19

Keywords

  • fiber lasers
  • mid-infrared lasers
  • supercontinuum generation
  • optical sensing
  • spectroscopy

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    Woodward, R. I., Majewski, M. R., Bharathan, G., Hudson, D. D., Fuerbach, A., & Jackson, S. D. (2019). Mid-infrared fiber sources for real-time biomedical sensing. In R. R. Alfano, S. G. Demos, & A. B. Seddon (Eds.), Optical Biopsy XVII: Toward Real-Time Spectroscopic Imaging and Diagnosis (pp. 1-8). [1087311] (Proceedings of SPIE; Vol. 10873). Piscataway, NJ: SPIE. https://doi.org/10.1117/12.2507322