Mini review

changes in the incidence of and progression to proliferative and sight-threatening diabetic retinopathy over the last 30 years

Gerald Liew, Vincent W. Wong, I-Van Ho

    Research output: Contribution to journalReview article

    25 Citations (Scopus)

    Abstract

    PURPOSE: Diabetic retinopathy is a leading cause of blindness worldwide. The last 3 decades have seen major improvements in glycemic and blood pressure control as well as the introduction of national screening programs, and we sought to determine if rates of proliferative diabetic retinopathy have changed as a result.

    METHODS: We conducted a systematic review to determine whether the incidence and progression rates of proliferative diabetic retinopathy and sight-threatening retinopathy have changed, focusing on large population-based studies with objective assessment of diabetic retinopathy.

    RESULTS: Comparisons across different studies is problematic due to different baseline retinopathy severity, different reported outcomes and different follow-up periods, but within these constraints certain trends could be identified. This review provides evidence that the incidence and progression of these conditions has reduced by approximately 2-3 fold over the last 3 decades.

    CONCLUSION: These results have implications for current diabetic retinopathy screening guidelines and has identified future areas where research could be improved.

    Original languageEnglish
    Pages (from-to)73-80
    Number of pages8
    JournalOphthalmic Epidemiology
    Volume24
    Issue number2
    Early online date19 Jan 2017
    DOIs
    Publication statusPublished - Apr 2017

    Keywords

    • diabetes
    • diabetic retinopathy
    • epidemiology
    • proliferative diabetic retinopathy
    • review

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