Missing internal limiting membrane during macular hole repair in Alport syndrome

Sarah G. Chaudhry, Gerald Liew, Adrian T. Fung*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)
12 Downloads (Pure)


The aim of this manuscript is to describe a novel retinal finding of Alport syndrome during surgical management of an associated macular hole. A retrospective chart review of a 65-year-old man with a diagnosis of Alport syndrome confirmed by renal biopsy was found to have an associated full-thickness macular hole. Pars-plana vitrectomy surgery with internal limiting membrane (ILM) peeling was attempted, but intraoperatively the ILM was found to be absent at the macula. Alport syndrome may be associated with the absence of the ILM. This can complicate attempts at macular hole repair.

Original languageEnglish
Pages (from-to)320-323
Number of pages4
JournalCase Reports in Ophthalmology
Issue number2
Publication statusPublished - 3 May 2021

Bibliographical note

Copyright the Author(s) 2021. Version archived for private and non-commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher.


  • Alport syndrome
  • Collagen IV
  • Inner limiting membrane
  • Macular hole surgery


Dive into the research topics of 'Missing internal limiting membrane during macular hole repair in Alport syndrome'. Together they form a unique fingerprint.

Cite this