Integrons and the site-specific recombination systems encoded by them provide a simple mechanism for the addition of new genes to bacterial chromosomes. Although there is substantial divergence among the four known integron-encoded integrases, they all recognize the recombination sites, known as 59-base elements, that are associated with genes that are packaged in gene cassettes. In contrast, the integron associated recombination sites, att1 sites, are preferentially recognized by the cognate integrase.
|Number of pages||13|
|Journal||Annals of the New York Academy of Sciences|
|Publication status||Published - May 1999|