Modelling errors in scoring the darkness of staining

T. Paul Hutchinson*, Sigurbjorg Gudlaugsdottir

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)


    OBJECTIVE: To construct a statistical model for the agreements and disagreements between two observers on darkness of staining. STUDY DESIGN: Data from an earlier observer-agreement study by van Diest et al were reanalyzed. RESULTS: A model in which the random variation in error is permitted to depend upon the true darkness of staining was found to fit the data much better than does one in which the random variation is constant. CONCLUSION: For the dataset analyzed, error tends to be greater (that is, correlation between observers tends to be less) when staining is darker.

    Original languageEnglish
    Pages (from-to)121-124
    Number of pages4
    JournalAnalytical and Quantitative Cytology and Histology
    Issue number2
    Publication statusPublished - 2002

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