Modelling problems in conservation genetics using Drosophila: consequences of fluctuating population sizes

L. M. Woodworth, M. E. Montgomery, R. K. Nurthen, D. A. Briscoe, R. Frankham*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

Many natural populations fluctuate widely in population size. This is predicted to reduce effective population size, genetic variation, and reproductive fitness, and to increase inbreeding. The effects of fluctuating population size were examined in small populations of Drosophila melanogaster of the same average size, but maintained using either fluctuating (FPS) or equal (EPS) population sizes.FPS lines were maintained using seven pairs and one pair in alternate generations, and EPS lines with four pairs per generation. Ten replicates of each treatment were maintained. After eight generations, FPS had a higher inbreeding coefficient than EPS (0.60 vs. 0.38), a lower average allozyme heterozygosity (0.068 vs. 0.131), and a much lower relative fitness (0.03 vs. 0.25). Estimates of effective population sizes for FPS and EPS were 3.8 and 7.9 from pedigree inbreeding, and 4.9 vs. 7.1 from changes in average heterozygosities, as compared to theoretical expectations of 3.3 vs. 8.0. Results were generally in accordance with theoretical predictions. Management strategies for populations of rare and endangered species should aim to minimize population fluctuations over generations.
Original languageEnglish
Pages (from-to)393-399
Number of pages7
JournalMolecular Ecology
Volume3
Issue number4
DOIs
Publication statusPublished - Aug 1994

Keywords

  • allozymes
  • conservation
  • effective population size
  • genetic variation
  • inbreeding depression
  • reproductive fitness

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