Modelling the number of dermal lesions in anthroponotic cutaneous leishmaniasis and its associated factors in Herat province, western Afghanistan, during 2012-2013

Eisa Nazar, Jamshid Yazdani Charati, Hossein Pazoki, Azadeh Saki*, Mahdi Fakhar, Farzaneh Boroumand, Sayed Abobakar Rasooli

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Cutaneous leishmaniasis (CL), caused byLeishmania tropica, is the main causative agent of CL in the Herat province, western Afghanistan. In CL patients, one of the most important indicators for reducing the amount of body damage and the choice of treatment is the number of dermal lesions, but there is no strong evidence in this regard. Therefore, using count regression models, the main objective of this historical cohort study was to identify the distribution of the number of dermal lesions and determine the associated factors among CL patients referring to leishmaniasis reference laboratory in Herat province, from January 2012 to December 2013. In a total of 4,127 clinically suspected CL cases, 50.20% were female and 49.80% male. Based on the results of ZINB model, which is the best model suggested by goodness-of-fit criteria, age variables (IRR = 1.007), duration of lesion (6-12 weeks compared to 12 weeks with IRR = 1.39 compared to

Original languageEnglish
Pages (from-to)2692-2701
Number of pages10
JournalTransboundary and Emerging Diseases
Volume67
Issue number6
Early online date13 May 2020
DOIs
Publication statusPublished - Nov 2020
Externally publishedYes

Keywords

  • anthroponotic cutaneous leishmaniasis
  • dermal lesions
  • Herat province
  • negative‐binomial regression model
  • Poisson regression model

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