Modulation of cellular viability

Stephanie Rayner; Albert Lee; Jennilee Davidson; Roger Chung

Modulation of cellular viability

Stephanie Rayner (Inventor), Albert Lee (Inventor), Jennilee Davidson (Inventor), Roger Chung (Inventor)

Research output: Patent

Abstract

Provided herein are methods for enhancing survival of a neuron, for inhibiting degeneration of a neuron, and for inhibiting abnormal protein accumulation in a neuron, optionally a motor neuron, comprising, consisting or consisting essentially of increasing the level of cyclin F in the neuron regardless of the neuron's level or activity of endogenous cyclin F. Optionally the neuron is in a subject with a neurodegenerative condition or at risk of developing a neurodegenerative condition, typically a neurodegenerative condition associated with a neuronal TDP-43 proteinopathy.

Original language	English
Patent number	AU2020369976
IPC	C12N 15/ 86 A I,A61K 48/00,A61P 25/28
Priority date	21/10/20
Filing date	21/10/20
Publication status	Published - 12 May 2022

Access to Document

https://ipsearch.ipaustralia.gov.au/patents/2020369976

4 Patent

Modulation of cellular viability
Rayner, S. (Inventor), Lee, A. (Inventor), Davidson, J. (Inventor) & Chung, R. (Inventor), 17 Nov 2022, IPC No. A61K 48/ 00 A I, Patent No. US2022362404, 21 Oct 2020, Priority date 21 Oct 2019, Priority No. AU2019903956
Research output: Patent

Open Access
Modulation of cellular viability
Rayner, S. (Inventor), Lee, A. (Inventor), Davidson, J. (Inventor) & Chung, R. (Inventor), 31 Aug 2022, IPC No. C12N 15/ 86 A I, C12N 15/18, A61K 48/00, A01K 67/027, A61P 25/28, Patent No. EP4048320, 21 Oct 2020, Priority date 21 Oct 2019, Priority No. AU2019903956
Research output: Patent

Open Access
Modulation of cellular viability
Rayner, S. (Inventor), Lee, A. (Inventor), Davidson, J. (Inventor) & Chung, R. (Inventor), 29 Apr 2021, (Submitted) IPC No. C12N 15/ 86 A I, A61K 48/00 2006.01, A61P 25/28 2006.01, Patent No. WO2021077162, Priority date 21 Oct 2019, Priority No. AU20190903956
Research output: Patent

Cite this

@misc{9ed888d5a92f42d7ae5dae39c55cc769,

title = "Modulation of cellular viability",

abstract = "Provided herein are methods for enhancing survival of a neuron, for inhibiting degeneration of a neuron, and for inhibiting abnormal protein accumulation in a neuron, optionally a motor neuron, comprising, consisting or consisting essentially of increasing the level of cyclin F in the neuron regardless of the neuron's level or activity of endogenous cyclin F. Optionally the neuron is in a subject with a neurodegenerative condition or at risk of developing a neurodegenerative condition, typically a neurodegenerative condition associated with a neuronal TDP-43 proteinopathy.",

author = "Stephanie Rayner and Albert Lee and Jennilee Davidson and Roger Chung",

year = "2022",

month = may,

day = "12",

language = "English",

type = "Patent",

note = "AU2020369976; C12N 15/ 86 A I,A61K 48/00,A61P 25/28",

}

TY - PAT

T1 - Modulation of cellular viability

AU - Rayner, Stephanie

AU - Lee, Albert

AU - Davidson, Jennilee

AU - Chung, Roger

PY - 2022/5/12

Y1 - 2022/5/12

N2 - Provided herein are methods for enhancing survival of a neuron, for inhibiting degeneration of a neuron, and for inhibiting abnormal protein accumulation in a neuron, optionally a motor neuron, comprising, consisting or consisting essentially of increasing the level of cyclin F in the neuron regardless of the neuron's level or activity of endogenous cyclin F. Optionally the neuron is in a subject with a neurodegenerative condition or at risk of developing a neurodegenerative condition, typically a neurodegenerative condition associated with a neuronal TDP-43 proteinopathy.

AB - Provided herein are methods for enhancing survival of a neuron, for inhibiting degeneration of a neuron, and for inhibiting abnormal protein accumulation in a neuron, optionally a motor neuron, comprising, consisting or consisting essentially of increasing the level of cyclin F in the neuron regardless of the neuron's level or activity of endogenous cyclin F. Optionally the neuron is in a subject with a neurodegenerative condition or at risk of developing a neurodegenerative condition, typically a neurodegenerative condition associated with a neuronal TDP-43 proteinopathy.

M3 - Patent

M1 - AU2020369976

Y2 - 2020/10/21

ER -

Modulation of cellular viability

Abstract

Access to Document

Fingerprint

Research output