TY - JOUR
T1 - Molecular changes in the adrenal medulla and brain following glucoprivation
AU - Goodchild, Ann K.
AU - Wisinski-Bokiniec, Phillip
AU - Hassan, Sarah F.
AU - Haynes, Paul
AU - Parker, Lindsay M.
AU - Vander Wall, Roshana
AU - Moghaddam, M.
AU - Mirzaei, Mehdi
PY - 2015
Y1 - 2015
N2 - Glucoprivation or hypoglycaemia evokes a complex array of counterregulatory responses which include autonomic, neuroendocrine and behavioural changes in order to maintain blood glucose levels. Catecholaminergic neurons of the rostral ventrolateral medulla activate adrenal adrenergic chromaffin cells to secrete adrenaline which mobilises glucose. Our aim was to determine the molecular changes and their timecourse in the adrenal medulla and brainstem regions in order to understand the cellular mechanisms altered in response to glucoprivation.
AB - Glucoprivation or hypoglycaemia evokes a complex array of counterregulatory responses which include autonomic, neuroendocrine and behavioural changes in order to maintain blood glucose levels. Catecholaminergic neurons of the rostral ventrolateral medulla activate adrenal adrenergic chromaffin cells to secrete adrenaline which mobilises glucose. Our aim was to determine the molecular changes and their timecourse in the adrenal medulla and brainstem regions in order to understand the cellular mechanisms altered in response to glucoprivation.
U2 - 10.1016/j.autneu.2015.07.394
DO - 10.1016/j.autneu.2015.07.394
M3 - Meeting abstract
VL - 192
SP - 45
EP - 46
JO - Autonomic Neuroscience: Basic and Clinical
JF - Autonomic Neuroscience: Basic and Clinical
SN - 1566-0702
T2 - Meeting of the International Society for Autonomic Neuroscience (ISAN) (9th : 2015)
Y2 - 26 September 2015 through 29 September 2015
ER -