Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections

Sam Abraham; Toni A. Chapman; Ben Ren Zhang; James Chin; Amanda N. Mabbett; Makrina Totsika; Mark A. Schembri

doi:10.1128/JCM.06671-11

Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections

Sam Abraham, Toni A. Chapman, Ben Ren Zhang, James Chin, Amanda N. Mabbett, Makrina Totsika, Mark A. Schembri^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

The differences between Escherichia coli strains associated with symptomatic and asymptomatic urinary tract infections (UTIs) remain to be properly determined. Here we examined the prevalence of plasmid types and bacteriocins, as well as genetic relatedness, in a defined collection of E. coli strains that cause UTIs. Comparative analysis identified a subgroup of strains with a high number of virulence genes (VGs) and microcins M/H47. We also identified associations between microcin genes, VGs, and specific plasmid types.

Original language	English
Pages (from-to)	1027-1030
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	50
Issue number	3
DOIs	https://doi.org/10.1128/JCM.06671-11
Publication status	Published - Mar 2012
Externally published	Yes

Keywords

VIRULENCE PROPERTIES
BACTERIURIA
AUSTRALIA
IDENTIFICATION
COMMENSALISM
UROPATHOGEN
PLASMIDS
ISLANDS
PCR

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10.1128/JCM.06671-11

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title = "Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections",

abstract = "The differences between Escherichia coli strains associated with symptomatic and asymptomatic urinary tract infections (UTIs) remain to be properly determined. Here we examined the prevalence of plasmid types and bacteriocins, as well as genetic relatedness, in a defined collection of E. coli strains that cause UTIs. Comparative analysis identified a subgroup of strains with a high number of virulence genes (VGs) and microcins M/H47. We also identified associations between microcin genes, VGs, and specific plasmid types.",

keywords = "VIRULENCE PROPERTIES, BACTERIURIA, AUSTRALIA, IDENTIFICATION, COMMENSALISM, UROPATHOGEN, PLASMIDS, ISLANDS, PCR",

author = "Sam Abraham and Chapman, {Toni A.} and Zhang, {Ben Ren} and James Chin and Mabbett, {Amanda N.} and Makrina Totsika and Schembri, {Mark A.}",

year = "2012",

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language = "English",

volume = "50",

pages = "1027--1030",

journal = "Journal of Clinical Microbiology",

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Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections. / Abraham, Sam; Chapman, Toni A.; Zhang, Ben Ren; Chin, James; Mabbett, Amanda N.; Totsika, Makrina; Schembri, Mark A.

In: Journal of Clinical Microbiology, Vol. 50, No. 3, 03.2012, p. 1027-1030.

Research output: Contribution to journal › Article › peer-review

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T1 - Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections

AU - Abraham, Sam

AU - Chapman, Toni A.

AU - Zhang, Ben Ren

AU - Chin, James

AU - Mabbett, Amanda N.

AU - Totsika, Makrina

AU - Schembri, Mark A.

PY - 2012/3

Y1 - 2012/3

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AB - The differences between Escherichia coli strains associated with symptomatic and asymptomatic urinary tract infections (UTIs) remain to be properly determined. Here we examined the prevalence of plasmid types and bacteriocins, as well as genetic relatedness, in a defined collection of E. coli strains that cause UTIs. Comparative analysis identified a subgroup of strains with a high number of virulence genes (VGs) and microcins M/H47. We also identified associations between microcin genes, VGs, and specific plasmid types.

KW - VIRULENCE PROPERTIES

KW - BACTERIURIA

KW - AUSTRALIA

KW - IDENTIFICATION

KW - COMMENSALISM

KW - UROPATHOGEN

KW - PLASMIDS

KW - ISLANDS

KW - PCR

U2 - 10.1128/JCM.06671-11

DO - 10.1128/JCM.06671-11

M3 - Article

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JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

SN - 0095-1137

IS - 3

ER -

Molecular characterization of Escherichia coli strains that cause symptomatic and asymptomatic urinary tract infections

Abstract

Keywords

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