Molecular characterization of Lactobacillus plantarum YML016 with anti-diabetic, anti-melanogenic and anti-viral efficacy

Vivek K. Bajpai; Rajib Majumder; Irfan A. Rather; Gyeong Jun Nam; Yong Ha Park

doi:10.1007/s40009-018-0659-5

Molecular characterization of Lactobacillus plantarum YML016 with anti-diabetic, anti-melanogenic and anti-viral efficacy

Vivek K. Bajpai, Rajib Majumder, Irfan A. Rather, Gyeong Jun Nam, Yong Ha Park^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The present study aimed to characterize a lactic acid bacterium Lactobacillus plantarum YML016 by 16 S rRNA gene sequencing and assessing its pharmacological potential in terms of α-glucosidase and tyrosinase inhibitory effects, as well as anti-viral efficacy against human pathogenic influenza A virus H1N1 using MDCK cell line. As a result, ethanolic extract of L. plantarum YML016 exhibited α-glucosidase and tyrosinase inhibitory activities by 95.83 and 73.59%, respectively in terms of its potent anti-diabetic and anti-melanogenic potential. Moreover, YML016 displayed profound anti-cytopathic effect on MDCK cell line when treated with ethanol extract (100 mg/ml) of YML016, confirming its potent anti-viral efficacy against H1N1 influenza A virus.

Original language	English
Pages (from-to)	301-305
Number of pages	5
Journal	National Academy Science Letters
Volume	41
Issue number	5
DOIs	https://doi.org/10.1007/s40009-018-0659-5
Publication status	Published - Oct 2018
Externally published	Yes

Keywords

Lactobacillus plantarum YML016
α-Glucosidase inhibitory activity
tyrosinase inhibitory activity
anti-viral activity

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10.1007/s40009-018-0659-5

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title = "Molecular characterization of Lactobacillus plantarum YML016 with anti-diabetic, anti-melanogenic and anti-viral efficacy",

abstract = "The present study aimed to characterize a lactic acid bacterium Lactobacillus plantarum YML016 by 16 S rRNA gene sequencing and assessing its pharmacological potential in terms of α-glucosidase and tyrosinase inhibitory effects, as well as anti-viral efficacy against human pathogenic influenza A virus H1N1 using MDCK cell line. As a result, ethanolic extract of L. plantarum YML016 exhibited α-glucosidase and tyrosinase inhibitory activities by 95.83 and 73.59%, respectively in terms of its potent anti-diabetic and anti-melanogenic potential. Moreover, YML016 displayed profound anti-cytopathic effect on MDCK cell line when treated with ethanol extract (100 mg/ml) of YML016, confirming its potent anti-viral efficacy against H1N1 influenza A virus.",

keywords = "Lactobacillus plantarum YML016, α-Glucosidase inhibitory activity, tyrosinase inhibitory activity, anti-viral activity",

author = "Bajpai, {Vivek K.} and Rajib Majumder and Rather, {Irfan A.} and Nam, {Gyeong Jun} and Park, {Yong Ha}",

year = "2018",

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doi = "10.1007/s40009-018-0659-5",

language = "English",

volume = "41",

pages = "301--305",

journal = "National Academy Science Letters",

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TY - JOUR

T1 - Molecular characterization of Lactobacillus plantarum YML016 with anti-diabetic, anti-melanogenic and anti-viral efficacy

AU - Bajpai, Vivek K.

AU - Majumder, Rajib

AU - Rather, Irfan A.

AU - Nam, Gyeong Jun

AU - Park, Yong Ha

PY - 2018/10

Y1 - 2018/10

N2 - The present study aimed to characterize a lactic acid bacterium Lactobacillus plantarum YML016 by 16 S rRNA gene sequencing and assessing its pharmacological potential in terms of α-glucosidase and tyrosinase inhibitory effects, as well as anti-viral efficacy against human pathogenic influenza A virus H1N1 using MDCK cell line. As a result, ethanolic extract of L. plantarum YML016 exhibited α-glucosidase and tyrosinase inhibitory activities by 95.83 and 73.59%, respectively in terms of its potent anti-diabetic and anti-melanogenic potential. Moreover, YML016 displayed profound anti-cytopathic effect on MDCK cell line when treated with ethanol extract (100 mg/ml) of YML016, confirming its potent anti-viral efficacy against H1N1 influenza A virus.

AB - The present study aimed to characterize a lactic acid bacterium Lactobacillus plantarum YML016 by 16 S rRNA gene sequencing and assessing its pharmacological potential in terms of α-glucosidase and tyrosinase inhibitory effects, as well as anti-viral efficacy against human pathogenic influenza A virus H1N1 using MDCK cell line. As a result, ethanolic extract of L. plantarum YML016 exhibited α-glucosidase and tyrosinase inhibitory activities by 95.83 and 73.59%, respectively in terms of its potent anti-diabetic and anti-melanogenic potential. Moreover, YML016 displayed profound anti-cytopathic effect on MDCK cell line when treated with ethanol extract (100 mg/ml) of YML016, confirming its potent anti-viral efficacy against H1N1 influenza A virus.

KW - Lactobacillus plantarum YML016

KW - α-Glucosidase inhibitory activity

KW - tyrosinase inhibitory activity

KW - anti-viral activity

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DO - 10.1007/s40009-018-0659-5

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JO - National Academy Science Letters

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IS - 5

ER -

Molecular characterization of Lactobacillus plantarum YML016 with anti-diabetic, anti-melanogenic and anti-viral efficacy

Abstract

Keywords

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