Molecular characterization of Lactobacillus plantarum YML016 with anti-diabetic, anti-melanogenic and anti-viral efficacy

Vivek K. Bajpai, Rajib Majumder, Irfan A. Rather, Gyeong Jun Nam, Yong Ha Park*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The present study aimed to characterize a lactic acid bacterium Lactobacillus plantarum YML016 by 16 S rRNA gene sequencing and assessing its pharmacological potential in terms of α-glucosidase and tyrosinase inhibitory effects, as well as anti-viral efficacy against human pathogenic influenza A virus H1N1 using MDCK cell line. As a result, ethanolic extract of L. plantarum YML016 exhibited α-glucosidase and tyrosinase inhibitory activities by 95.83 and 73.59%, respectively in terms of its potent anti-diabetic and anti-melanogenic potential. Moreover, YML016 displayed profound anti-cytopathic effect on MDCK cell line when treated with ethanol extract (100 mg/ml) of YML016, confirming its potent anti-viral efficacy against H1N1 influenza A virus.

Original languageEnglish
Pages (from-to)301-305
Number of pages5
JournalNational Academy Science Letters
Volume41
Issue number5
DOIs
Publication statusPublished - Oct 2018
Externally publishedYes

Keywords

  • Lactobacillus plantarum YML016
  • α-Glucosidase inhibitory activity
  • tyrosinase inhibitory activity
  • anti-viral activity

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