Monitoring of anaesthesia in neurophysiological experiments

A. Kral, J. Tillein, R. Hartmann, R. Klinke*

*Corresponding author for this work

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Cortical activity can be substantially changed by the type of anaesthetic used, and by its dose level. For easy monitoring of depth of anaesthesia we describe the changes in electroencephalogram and electrocardiogram accompanying changes in depth of anaesthesia in the cat. Anaesthesia was induced by the volatile anaesthetic isoflurane. The high- frequency components (around 30 Hz) in the electroencephalogram disappear in deep anaesthesia. The electrocardiogram also shows substantial changes in contamination due to muscle fasciculations with anaesthesia level. Fasciculations appear as noise in the electrocardiogram. The amplitude of the electrical muscle activity contaminating the ECG can be easily used for the maintainance of a constant level of anaesthesia during a neurophysiological experiment.

Original languageEnglish
Pages (from-to)781-787
Number of pages7
JournalNeuroReport
Volume10
Issue number4
DOIs
Publication statusPublished - 17 Mar 1999
Externally publishedYes

Keywords

  • Anaesthesia
  • Cortex
  • ECG
  • EEG
  • Field potentials
  • Muscle activity
  • Neurophysiology

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