TY - JOUR
T1 - Mood state as a predictor of neuropsychological deficits following cardiac surgery
AU - Andrew, Marie J.
AU - Baker, Robert A.
AU - Kneebone, Anthony C.
AU - Knight, John L.
PY - 2000
Y1 - 2000
N2 - Objectives: Mood disorders and neuropsychological deficits are both commonly reported occurrences after cardiac surgery. We examined the relationship between mood state and postoperative cognitive deficits in this population. Methods: Assessments of neuropsychological functions and mood state (depression, anxiety, stress scales; DASS) were performed preoperatively and postoperatively on 147 patients undergoing cardiac surgery. Results: The incidence of preoperative depression, anxiety, and stress symptomatology was 16%, 27%, and 16%, respectively. The incidence of postoperative anxiety symptomatology significantly increased to 45% (p < 0.001), while the incidence of depression and stress symptomatology remained stable (19% and 15%, respectively; ns). Changes in mood state did not influence changes in neuropsychological performance. Preoperative mood was a strong predictor of postoperative mood, and was related to postoperative deficits on measures of attention and memory. Conclusions: An assessment of preoperative mood is critical in identifying patients at risk of postoperative mood disorders and neuropsychological deficits. Measures assessing somatic manifestations of anxiety may not be suitable for a surgical population. (C) 2000 Elsevier Science Inc. All rights reserved.
AB - Objectives: Mood disorders and neuropsychological deficits are both commonly reported occurrences after cardiac surgery. We examined the relationship between mood state and postoperative cognitive deficits in this population. Methods: Assessments of neuropsychological functions and mood state (depression, anxiety, stress scales; DASS) were performed preoperatively and postoperatively on 147 patients undergoing cardiac surgery. Results: The incidence of preoperative depression, anxiety, and stress symptomatology was 16%, 27%, and 16%, respectively. The incidence of postoperative anxiety symptomatology significantly increased to 45% (p < 0.001), while the incidence of depression and stress symptomatology remained stable (19% and 15%, respectively; ns). Changes in mood state did not influence changes in neuropsychological performance. Preoperative mood was a strong predictor of postoperative mood, and was related to postoperative deficits on measures of attention and memory. Conclusions: An assessment of preoperative mood is critical in identifying patients at risk of postoperative mood disorders and neuropsychological deficits. Measures assessing somatic manifestations of anxiety may not be suitable for a surgical population. (C) 2000 Elsevier Science Inc. All rights reserved.
KW - Anxiety
KW - Cardiac surgery
KW - Depression
KW - Mood
KW - Neuropsychological deficits
KW - Stress
UR - http://www.scopus.com/inward/record.url?scp=0033814672&partnerID=8YFLogxK
U2 - 10.1016/S0022-3999(00)00089-1
DO - 10.1016/S0022-3999(00)00089-1
M3 - Article
C2 - 11033372
AN - SCOPUS:0033814672
SN - 0022-3999
VL - 48
SP - 537
EP - 546
JO - Journal of Psychosomatic Research
JF - Journal of Psychosomatic Research
IS - 6
ER -