TY - JOUR
T1 - Morphometric and mechanical evaluation of titanium implant integration
T2 - Comparison of five surface structures
AU - Svehla, M.
AU - Morberg, P.
AU - Zicat, B.
AU - Bruce, W.
AU - Sonnabend, D.
AU - Walsh, W. R.
PY - 2000
Y1 - 2000
N2 - Achieving a stable bone-implant interface is an important factor in the long-term outcome of joint arthroplasty. In this study, we employed an ovine bicortical model to compare the bone-healing response to five different surfaces on titanium alloy implants: grit blasted (GB), grit blasted plus hydroxyapatite (50 μm thick) coating (GBHA), Porocoat® (PC), Porocoat® with HA (PCHA) and smooth (S). Push-out testing, histology, and backscatter scanning electron microscope (SEM) imaging were employed to assess the healing response at 4, 8, and 12 weeks. Push-out testing revealed PC and PCHA surfaces resulted in significantly greater mechanical fixation over all other implant types at all time points (p <. 05). HA coating on the grit-blasted surface significantly improved fixation at 8 and 12 weeks (p < .05). The addition of HA onto the porous coating did not significantly improve fixation in this model. Quantification of ingrowth/ongrowth from SEM images revealed that HA coating of the grit-blasted surfaces resulted in significantly more ongrowth at 4 weeks (p < .05). (C) 2000 John Wiley and Sons, Inc.
AB - Achieving a stable bone-implant interface is an important factor in the long-term outcome of joint arthroplasty. In this study, we employed an ovine bicortical model to compare the bone-healing response to five different surfaces on titanium alloy implants: grit blasted (GB), grit blasted plus hydroxyapatite (50 μm thick) coating (GBHA), Porocoat® (PC), Porocoat® with HA (PCHA) and smooth (S). Push-out testing, histology, and backscatter scanning electron microscope (SEM) imaging were employed to assess the healing response at 4, 8, and 12 weeks. Push-out testing revealed PC and PCHA surfaces resulted in significantly greater mechanical fixation over all other implant types at all time points (p <. 05). HA coating on the grit-blasted surface significantly improved fixation at 8 and 12 weeks (p < .05). The addition of HA onto the porous coating did not significantly improve fixation in this model. Quantification of ingrowth/ongrowth from SEM images revealed that HA coating of the grit-blasted surfaces resulted in significantly more ongrowth at 4 weeks (p < .05). (C) 2000 John Wiley and Sons, Inc.
KW - Bone
KW - Hydroxyapatite
KW - Ingrowth/ongrowth
KW - Porous surface
KW - Push-out
UR - http://www.scopus.com/inward/record.url?scp=0034038825&partnerID=8YFLogxK
U2 - 10.1002/(SICI)1097-4636(200007)51:1<15::AID-JBM3>3.0.CO;2-9
DO - 10.1002/(SICI)1097-4636(200007)51:1<15::AID-JBM3>3.0.CO;2-9
M3 - Article
C2 - 10813740
AN - SCOPUS:0034038825
SN - 0021-9304
VL - 51
SP - 15
EP - 22
JO - Journal of Biomedical Materials Research
JF - Journal of Biomedical Materials Research
IS - 1
ER -