Achieving a stable bone-implant interface is an important factor in the long-term outcome of joint arthroplasty. In this study, we employed an ovine bicortical model to compare the bone-healing response to five different surfaces on titanium alloy implants: grit blasted (GB), grit blasted plus hydroxyapatite (50 μm thick) coating (GBHA), Porocoat® (PC), Porocoat® with HA (PCHA) and smooth (S). Push-out testing, histology, and backscatter scanning electron microscope (SEM) imaging were employed to assess the healing response at 4, 8, and 12 weeks. Push-out testing revealed PC and PCHA surfaces resulted in significantly greater mechanical fixation over all other implant types at all time points (p <. 05). HA coating on the grit-blasted surface significantly improved fixation at 8 and 12 weeks (p < .05). The addition of HA onto the porous coating did not significantly improve fixation in this model. Quantification of ingrowth/ongrowth from SEM images revealed that HA coating of the grit-blasted surfaces resulted in significantly more ongrowth at 4 weeks (p < .05). (C) 2000 John Wiley and Sons, Inc.
|Number of pages||8|
|Journal||Journal of Biomedical Materials Research|
|Publication status||Published - 2000|
- Porous surface