Skip to main navigation Skip to search Skip to main content

Mouse brain glycomics – Insights from exploring the Allen Brain Atlas and the implications for the neuroimmune brain

Edward S. X. Moh, Sagar Dalal, Mark R. Hutchinson, Nicolle H. Packer*

*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4   Link opens in a new tab Citations (Scopus)

Abstract

The Allen Institute Mouse Brain Atlas, with visualisation using the Brain Explorer software, offers a 3-dimensional view of region-specific RNA expression of thousands of mouse genes. In this Viewpoint, we focused on the region-specific expression of genes related to cellular glycosylation, and discuss their relevance towards psychoneuroimmunology. Using specific examples, we show that the Atlas validates existing observations reported by others, identifies previously unknown potential region-specific glycan features, and highlights the need to promote collaborations between glycobiology and psychoneuroimmunology researchers.
Original languageEnglish
Pages (from-to)83-90
Number of pages8
JournalBrain, Behavior, and Immunity
Volume113
Early online date30 Jun 2023
DOIs
Publication statusPublished - Oct 2023

Keywords

  • Glycosylation
  • Allen Brain
  • region-specific
  • psychoneuroimmunology
  • Data mining
  • Region-specific
  • Psychoneuroimmunology

Access to Document

Other files and links

Fingerprint

Dive into the research topics of 'Mouse brain glycomics – Insights from exploring the Allen Brain Atlas and the implications for the neuroimmune brain'. Together they form a unique fingerprint.
View full fingerprint

  • COESB: ARC Centre of Excellence in Synthetic Biology

    Paulsen, I. (Primary Chief Investigator), Filipovska, A. (Chief Investigator), Parker, R. (Chief Investigator), Nielsen, L. K. (Chief Investigator), Neilan, B. A. (Chief Investigator), Alexandrov, K. (Chief Investigator), Jackson , C. (Chief Investigator), Wodak, J. (Chief Investigator), Rackham, O. (Chief Investigator), Marcellin, E. (Chief Investigator), Gillings, M. (Chief Investigator), Rogers, W. (Chief Investigator), Lee, L. (Chief Investigator), Packer, N. (Chief Investigator), O'Hara, I. M. (Chief Investigator), Speight, R. (Chief Investigator), Vickers, C. E. (Chief Investigator), Beliaev, A. (Chief Investigator), Scott, C. (Partner Investigator), Lacey, J. (Partner Investigator), Mankad, A. (Partner Investigator), Calvert, J. (Partner Investigator), Thomas, G. (Partner Investigator), Rodriguez-Concepcion, M. (Partner Investigator), Fleishman, S. (Partner Investigator), Koepke, M. (Partner Investigator), Ball, M. (Partner Investigator), Turner, N. J. (Partner Investigator), Borneman, A. R. (Partner Investigator), Holowko, M. (Partner Investigator), Goold, H. (Partner Investigator), Ellis, T. (Partner Investigator), Mitchell, L. A. (Partner Investigator) & Dai, J. (Partner Investigator)

    9/11/20 → 8/11/27

    Project: Research

Cite this