Multi-branched model of the human arterial system

A. P. Avolio*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

407 Citations (Scopus)

Abstract

A model of the human arterial system was constructed based on the anatomical branching structure of the arterial tree. Arteries were divided into segments represented by uniform thin-walled elastic tubes with realistic arterial dimensions and wall properties. The configuration contains 128 segments accounting for all the central vessels and major peripheral arteries supplying the extremities including vessels of the order of 2·0 mm diameter. Vascular impedance and pressure and flow waveforms were determined at various locations in the system and good agreement was found with experimental measurements. Use of the model is illustrated in investigating wave propagation in the arterial system and in simulation of arterial dynamics in such pathological conditions as arteriosclerosis and presence of a stenosis in the femoral artery.

Original languageEnglish
Pages (from-to)709-718
Number of pages10
JournalMedical & Biological Engineering & Computing
Volume18
Issue number6
DOIs
Publication statusPublished - Nov 1980
Externally publishedYes

Keywords

  • Arterial branching
  • Arterial model
  • Elastic tubes
  • Vascular impedance
  • Wave reflection

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