Multiplex suspension assay/array using lifetime coding

Dayong Jin (Inventor), Yiqing Lu (Inventor), Jiangbo Zhao (Inventor)

Research output: Patent

Abstract

A system, device and/or method for multiplex assays are provided. In a particular, but non-limiting, example there is provided a multiplex array, such as a suspension array. Luminescence decay lifetimes are utilized for probes in a suspension array, and coding/decoding the codes from time-resolved spectra. Lifetime populations can be generated at distinct color bands. A novel temporal technique or dimension is applied over conventional spectral and intensity combinations, thereby expanding the multiplexing capacity of a suspension array. In one example form, the multiplexing capacity of a suspension array can be expanded to the order of about 58. This provides a reliable, high-throughput and relatively inexpensive solution for multiplex assays in various areas of application such as life sciences, data storage and security.

Original languageEnglish
Patent number104641233
IPCG01N 33/53,G01N 21/64,C09K 11/77,B82Y 15/00,G01N 33/543,C40B 70/00
Priority date22/06/12
Publication statusPublished - 9 Jan 2018

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