Multiplex suspension assay/array using lifetime coding

Dayong Jin; Yiqing Lu; Jiangbo Zhao

Multiplex suspension assay/array using lifetime coding

Dayong Jin (Inventor), Yiqing Lu (Inventor), Jiangbo Zhao (Inventor)

Research output: Patent

Abstract

A system, device and/or method for multiplex assays. In a particular, but non-limiting, example there is provided a multiplex array, such as a suspension array. Luminescence decay lifetimes are utilised for probes in a suspension array, and coding/decoding the codes from time-resolved spectra. Lifetime populations can be generated at distinct colour bands. A novel temporal technique or dimension is applied over conventional spectral and intensity combinations, thereby expanding the multiplexing capacity of a suspension array. In one example form, the multiplexing capacity of a suspension array can be expanded to the order of about 5⁸. This provides a reliable, high-throughput and relatively inexpensive solution for multiplex assays in various areas of application such as life sciences, data storage and security.

Original language	English
Patent number	WO2013188927
IPC	G01N 33/53 2006.01,G01N 21/64 2006.01,C09K 11/77 2006.01,B82Y 15/00 2011.01,G01N 33/543 2006.01,C40B 70/00 2006.01,C12M 1/34 2006.01
Priority date	22/06/12
Filing date	21/06/13
Publication status	Submitted - 27 Dec 2013

Bibliographical note

Designated States
AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)

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5 Patent

Multiplex suspension assay/array using lifetime coding
Jin, D., Lu, Y. & Zhao, J., 25 Oct 2018, IPC No. G01N 33/53, B82Y 15/00, C09K 11/77, C12M 1/34, C40B 70/00, G01N 21/64, Patent No. 2013277946, Priority date 22 Jun 2012, Priority No. AU2012902652
Research output: Patent

Open Access
Multiplex suspension assay/array using lifetime coding
Jin, D., Lu, Y. & Zhao, J., 9 Jan 2018, IPC No. G01N 33/53, G01N 21/64, C09K 11/77, B82Y 15/00, G01N 33/543, C40B 70/00, Patent No. 104641233, Priority date 22 Jun 2012, Priority No. AU2012902652
Research output: Patent

Open Access
Multiplex suspension assay/array using lifetime coding
Jin, D., Lu, Y. & Zhao, J., 14 Nov 2017, IPC No. G01N 21/64, C40B 70/00, C09K 11/02, C09K 11/06, C09D 11/50, C09K 11/77, Patent No. 09816926, Priority date 22 Jun 2012, Priority No. AU2012902652
Research output: Patent

Open Access

Cite this

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title = "Multiplex suspension assay/array using lifetime coding",

abstract = "A system, device and/or method for multiplex assays. In a particular, but non-limiting, example there is provided a multiplex array, such as a suspension array. Luminescence decay lifetimes are utilised for probes in a suspension array, and coding/decoding the codes from time-resolved spectra. Lifetime populations can be generated at distinct colour bands. A novel temporal technique or dimension is applied over conventional spectral and intensity combinations, thereby expanding the multiplexing capacity of a suspension array. In one example form, the multiplexing capacity of a suspension array can be expanded to the order of about 58. This provides a reliable, high-throughput and relatively inexpensive solution for multiplex assays in various areas of application such as life sciences, data storage and security.",

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PY - 2013/12/27

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N2 - A system, device and/or method for multiplex assays. In a particular, but non-limiting, example there is provided a multiplex array, such as a suspension array. Luminescence decay lifetimes are utilised for probes in a suspension array, and coding/decoding the codes from time-resolved spectra. Lifetime populations can be generated at distinct colour bands. A novel temporal technique or dimension is applied over conventional spectral and intensity combinations, thereby expanding the multiplexing capacity of a suspension array. In one example form, the multiplexing capacity of a suspension array can be expanded to the order of about 58. This provides a reliable, high-throughput and relatively inexpensive solution for multiplex assays in various areas of application such as life sciences, data storage and security.

AB - A system, device and/or method for multiplex assays. In a particular, but non-limiting, example there is provided a multiplex array, such as a suspension array. Luminescence decay lifetimes are utilised for probes in a suspension array, and coding/decoding the codes from time-resolved spectra. Lifetime populations can be generated at distinct colour bands. A novel temporal technique or dimension is applied over conventional spectral and intensity combinations, thereby expanding the multiplexing capacity of a suspension array. In one example form, the multiplexing capacity of a suspension array can be expanded to the order of about 58. This provides a reliable, high-throughput and relatively inexpensive solution for multiplex assays in various areas of application such as life sciences, data storage and security.

M3 - Patent

M1 - WO2013188927

Y2 - 2013/06/21

ER -

Multiplex suspension assay/array using lifetime coding

Abstract

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