Multiplex suspension assay/array using lifetime coding

Dayong Jin; Yiqing Lu; Jiangbo Zhao

Multiplex suspension assay/array using lifetime coding

Dayong Jin (Inventor), Yiqing Lu (Inventor), Jiangbo Zhao (Inventor)

Research output: Patent

Abstract

A system, device and/or method for multiplex assays. In a particular, but non-limiting, example there is provided a multiplex array, such as a suspension array. Luminescence decay lifetimes are utilised for probes in a suspension array, and coding/decoding the codes from time-resolved spectra. Lifetime populations can be generated at distinct colour bands. A novel temporal technique or dimension is applied over conventional spectral and intensity combinations, thereby expanding the multiplexing capacity of a suspension array. In one example form, the multiplexing capacity of a suspension array can be expanded to the order of about 5⁸. This provides a reliable, high-throughput and relatively inexpensive solution for multiplex assays in various areas of application such as life sciences, data storage and security.

Original language	English
Patent number	2013277946
IPC	G01N 33/53,B82Y 15/00,C09K 11/77,C12M 1/34,C40B 70/00,G01N 21/64
Priority date	22/06/12
Publication status	Published - 25 Oct 2018

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Multiplex suspension assay/array using lifetime coding
Jin, D., Lu, Y. & Zhao, J., 9 Jan 2018, IPC No. G01N 33/53, G01N 21/64, C09K 11/77, B82Y 15/00, G01N 33/543, C40B 70/00, Patent No. 104641233, Priority date 22 Jun 2012, Priority No. AU2012902652
Research output: Patent

Open Access
Multiplex suspension assay/array using lifetime coding
Jin, D., Lu, Y. & Zhao, J., 14 Nov 2017, IPC No. G01N 21/64, C40B 70/00, C09K 11/02, C09K 11/06, C09D 11/50, C09K 11/77, Patent No. 09816926, Priority date 22 Jun 2012, Priority No. AU2012902652
Research output: Patent

Open Access
Multiplex suspension assay/array using lifetime coding
Jin, D., Lu, Y. & Zhao, J., 24 Jul 2015, (Submitted) IPC No. G01N 33/53, G01N 21/64, C09K 11/77, Patent No. 2559MUMNP2014, Priority date 22 Jun 2012, Priority No. AU2012902652
Research output: Patent

Cite this

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title = "Multiplex suspension assay/array using lifetime coding",

abstract = "A system, device and/or method for multiplex assays. In a particular, but non-limiting, example there is provided a multiplex array, such as a suspension array. Luminescence decay lifetimes are utilised for probes in a suspension array, and coding/decoding the codes from time-resolved spectra. Lifetime populations can be generated at distinct colour bands. A novel temporal technique or dimension is applied over conventional spectral and intensity combinations, thereby expanding the multiplexing capacity of a suspension array. In one example form, the multiplexing capacity of a suspension array can be expanded to the order of about 58. This provides a reliable, high-throughput and relatively inexpensive solution for multiplex assays in various areas of application such as life sciences, data storage and security.",

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N2 - A system, device and/or method for multiplex assays. In a particular, but non-limiting, example there is provided a multiplex array, such as a suspension array. Luminescence decay lifetimes are utilised for probes in a suspension array, and coding/decoding the codes from time-resolved spectra. Lifetime populations can be generated at distinct colour bands. A novel temporal technique or dimension is applied over conventional spectral and intensity combinations, thereby expanding the multiplexing capacity of a suspension array. In one example form, the multiplexing capacity of a suspension array can be expanded to the order of about 58. This provides a reliable, high-throughput and relatively inexpensive solution for multiplex assays in various areas of application such as life sciences, data storage and security.

AB - A system, device and/or method for multiplex assays. In a particular, but non-limiting, example there is provided a multiplex array, such as a suspension array. Luminescence decay lifetimes are utilised for probes in a suspension array, and coding/decoding the codes from time-resolved spectra. Lifetime populations can be generated at distinct colour bands. A novel temporal technique or dimension is applied over conventional spectral and intensity combinations, thereby expanding the multiplexing capacity of a suspension array. In one example form, the multiplexing capacity of a suspension array can be expanded to the order of about 58. This provides a reliable, high-throughput and relatively inexpensive solution for multiplex assays in various areas of application such as life sciences, data storage and security.

M3 - Patent

M1 - 2013277946

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Multiplex suspension assay/array using lifetime coding

Abstract

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