Mutations to the ALS/FTD gene CCNF reveals elevated Lys48-linked ubiquitination by the SCF(cyclin F) complex

Research output

Research output per year 2017 2017 2018 2019 2019

• 2 Abstract
• 1 Article

Research output per year

Research output per year

Search results

• 2018

  Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

  Lee, A., Rayner, S. L., Gwee, S. S. L., De Luca, A., Shahheydari, H., Sundaramoorthy, V., Ragagnin, A., Morsch, M., Radford, R., Galper, J., Freckleton, S., Shi, B., Walker, A. K., Don, E. K., Cole, N. J., Yang, S., Williams, K. L., Yerbury, J. J., Blair, I. P., Atkin, J. D., & 2 othersMolloy, M. P. & Chung, R. S., Jan 2018, In: Cellular and Molecular Life Sciences. 75, 2, p. 335–354 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Frontotemporal Dementia With Motor Neuron Disease 100%
  • Cyclins 78%
  • Ubiquitination 70%
  • Autophagy 62%
  • Mutation 36%
  39 Citations (Scopus)