Methods are described for accessing the little known class of 4-alkyliminoquinoline-3-carboxamide title compounds 4; viz., from 4-oxoquinoline-3-carboxylic acids treated successively with thionyl chloride and amine, from 4-oxoquinoline-3-carboxylic esters treated likewise, and from the hydrogen chloride salt of a 4-alkyliminoquinoline-3-carboxylic ester and amine. Mechanistic aspects of the syntheses are discussed, and some spectroscopic and chemical properties of the title compounds are presented.
|Number of pages||16|
|Journal||South African Journal of Chemistry|
|Publication status||Published - 25 Sep 2001|