Abstract
Methods are described for accessing the little known class of 4-alkyliminoquinoline-3-carboxamide title compounds 4; viz., from 4-oxoquinoline-3-carboxylic acids treated successively with thionyl chloride and amine, from 4-oxoquinoline-3-carboxylic esters treated likewise, and from the hydrogen chloride salt of a 4-alkyliminoquinoline-3-carboxylic ester and amine. Mechanistic aspects of the syntheses are discussed, and some spectroscopic and chemical properties of the title compounds are presented.
Original language | English |
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Pages (from-to) | 102-117 |
Number of pages | 16 |
Journal | South African Journal of Chemistry |
Volume | 54 |
Publication status | Published - 25 Sept 2001 |
Keywords
- Mechanism
- Quinolin-4-imines
- Quinolin-4-ones