N,1-dialkyl-7-(alkylamino)-4-(alkylimino)-1,4-dihydroquinoline-3- carboxamides and their 4-oxo derivatives: Synthesis and properties

Theodorus Van Es; Benjamin Staskun

N,1-dialkyl-7-(alkylamino)-4-(alkylimino)-1,4-dihydroquinoline-3- carboxamides and their 4-oxo derivatives: Synthesis and properties

Theodorus Van Es, Benjamin Staskun^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Methods are described for accessing the little known class of 4-alkyliminoquinoline-3-carboxamide title compounds 4; viz., from 4-oxoquinoline-3-carboxylic acids treated successively with thionyl chloride and amine, from 4-oxoquinoline-3-carboxylic esters treated likewise, and from the hydrogen chloride salt of a 4-alkyliminoquinoline-3-carboxylic ester and amine. Mechanistic aspects of the syntheses are discussed, and some spectroscopic and chemical properties of the title compounds are presented.

Original language	English
Pages (from-to)	102-117
Number of pages	16
Journal	South African Journal of Chemistry
Volume	54
Publication status	Published - 25 Sept 2001

Keywords

Mechanism
Quinolin-4-imines
Quinolin-4-ones

Cite this

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title = "N,1-dialkyl-7-(alkylamino)-4-(alkylimino)-1,4-dihydroquinoline-3- carboxamides and their 4-oxo derivatives: Synthesis and properties",

abstract = "Methods are described for accessing the little known class of 4-alkyliminoquinoline-3-carboxamide title compounds 4; viz., from 4-oxoquinoline-3-carboxylic acids treated successively with thionyl chloride and amine, from 4-oxoquinoline-3-carboxylic esters treated likewise, and from the hydrogen chloride salt of a 4-alkyliminoquinoline-3-carboxylic ester and amine. Mechanistic aspects of the syntheses are discussed, and some spectroscopic and chemical properties of the title compounds are presented.",

keywords = "Mechanism, Quinolin-4-imines, Quinolin-4-ones",

author = "{Van Es}, Theodorus and Benjamin Staskun",

year = "2001",

month = sep,

day = "25",

language = "English",

volume = "54",

pages = "102--117",

journal = "South African Journal of Chemistry",

issn = "0379-4350",

publisher = "Bureau for Scientific Publications",

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TY - JOUR

T1 - N,1-dialkyl-7-(alkylamino)-4-(alkylimino)-1,4-dihydroquinoline-3- carboxamides and their 4-oxo derivatives

T2 - Synthesis and properties

AU - Van Es, Theodorus

AU - Staskun, Benjamin

PY - 2001/9/25

Y1 - 2001/9/25

N2 - Methods are described for accessing the little known class of 4-alkyliminoquinoline-3-carboxamide title compounds 4; viz., from 4-oxoquinoline-3-carboxylic acids treated successively with thionyl chloride and amine, from 4-oxoquinoline-3-carboxylic esters treated likewise, and from the hydrogen chloride salt of a 4-alkyliminoquinoline-3-carboxylic ester and amine. Mechanistic aspects of the syntheses are discussed, and some spectroscopic and chemical properties of the title compounds are presented.

AB - Methods are described for accessing the little known class of 4-alkyliminoquinoline-3-carboxamide title compounds 4; viz., from 4-oxoquinoline-3-carboxylic acids treated successively with thionyl chloride and amine, from 4-oxoquinoline-3-carboxylic esters treated likewise, and from the hydrogen chloride salt of a 4-alkyliminoquinoline-3-carboxylic ester and amine. Mechanistic aspects of the syntheses are discussed, and some spectroscopic and chemical properties of the title compounds are presented.

KW - Mechanism

KW - Quinolin-4-imines

KW - Quinolin-4-ones

UR - http://www.scopus.com/inward/record.url?scp=4243053162&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:4243053162

SN - 0379-4350

VL - 54

SP - 102

EP - 117

JO - South African Journal of Chemistry

JF - South African Journal of Chemistry

ER -

N,1-dialkyl-7-(alkylamino)-4-(alkylimino)-1,4-dihydroquinoline-3- carboxamides and their 4-oxo derivatives: Synthesis and properties

Abstract

Keywords

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