N,1-dialkyl-7-(alkylamino)-4-(alkylimino)-1,4-dihydroquinoline-3- carboxamides and their 4-oxo derivatives: Synthesis and properties

Theodorus Van Es, Benjamin Staskun*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    2 Citations (Scopus)


    Methods are described for accessing the little known class of 4-alkyliminoquinoline-3-carboxamide title compounds 4; viz., from 4-oxoquinoline-3-carboxylic acids treated successively with thionyl chloride and amine, from 4-oxoquinoline-3-carboxylic esters treated likewise, and from the hydrogen chloride salt of a 4-alkyliminoquinoline-3-carboxylic ester and amine. Mechanistic aspects of the syntheses are discussed, and some spectroscopic and chemical properties of the title compounds are presented.

    Original languageEnglish
    Pages (from-to)102-117
    Number of pages16
    JournalSouth African Journal of Chemistry
    Publication statusPublished - 25 Sept 2001


    • Mechanism
    • Quinolin-4-imines
    • Quinolin-4-ones


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