Nailfold capillary circulation in osteoarthritis

R. O. Day*, T. Wacher, D. Cairns, G. Conners, M. Mcgrath

*Corresponding author for this work

    Research output: Contribution to journalArticle

    3 Citations (Scopus)

    Abstract

    Nailfold capillaries in 28 patients with OA affecting the distal interphalangeal joints were compared to 23 age-and sex matched controls without OA. Patients with OA showed a significantly lower density of capillaries in their nailfolds and significantly more capillary morphological abnormalities including haemorrhage, 'drop out' , dilatation and irregularity. There was a trend for OA patients to have warmer fingers with reduced finger to brachial blood pressure ratios. There were significant correlations between nailfold capillary numbers and average joint tenderness and between capillary morphological changes and joint swelling. These results reveal a relationship between interphalangeal joint OA and nailfold capillary abnormalities and density. As changes in microcirculation may be pertinent to the pathogenesis of OA, further studies which could explore possible causal relationships are warranted.

    Original languageEnglish
    Pages (from-to)1062-1065
    Number of pages4
    JournalRheumatology
    Volume32
    Issue number12
    DOIs
    Publication statusPublished - Dec 1993

    Keywords

    • Microcirculation
    • Nailford capillaries
    • Osteoarthritis

    Fingerprint Dive into the research topics of 'Nailfold capillary circulation in osteoarthritis'. Together they form a unique fingerprint.

    Cite this