Nails: Concern over their use in lead exposure assessment

Brian L. Gulson

doi:10.1016/0048-9697(95)04896-0

Nails: Concern over their use in lead exposure assessment

Brian L. Gulson^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

Non-invasive procedures for determination of lead exposure such as nails or hair are an attractive alternative to more invasive procedures, such as blood sampling, especially for infants. In spite of rigorous sample preparation and use of high precision lead isotope measurements, data obtained for fingernails and toenails of a subject serially sampled for over 6 months and in several other subjects exhibit such variability as to preclude nails as a reliable lead exposure indicator.

Original language	English
Pages (from-to)	323-327
Number of pages	5
Journal	Science of the Total Environment
Volume	177
DOIs	https://doi.org/10.1016/0048-9697(95)04896-0
Publication status	Published - 5 Jan 1996

Keywords

blood Pb
human nail
lead exposure assessment
lead isotopes

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10.1016/0048-9697(95)04896-0

Cite this

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abstract = "Non-invasive procedures for determination of lead exposure such as nails or hair are an attractive alternative to more invasive procedures, such as blood sampling, especially for infants. In spite of rigorous sample preparation and use of high precision lead isotope measurements, data obtained for fingernails and toenails of a subject serially sampled for over 6 months and in several other subjects exhibit such variability as to preclude nails as a reliable lead exposure indicator.",

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AB - Non-invasive procedures for determination of lead exposure such as nails or hair are an attractive alternative to more invasive procedures, such as blood sampling, especially for infants. In spite of rigorous sample preparation and use of high precision lead isotope measurements, data obtained for fingernails and toenails of a subject serially sampled for over 6 months and in several other subjects exhibit such variability as to preclude nails as a reliable lead exposure indicator.

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KW - human nail

KW - lead exposure assessment

KW - lead isotopes

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JO - Science of the Total Environment

JF - Science of the Total Environment

ER -

Nails: Concern over their use in lead exposure assessment

Abstract

Keywords

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