Abstract
Simultaneous multi-element imaging using NanoSIMS (nano-scale secondary ion mass spectrometry), exploiting the novel combination of 195Pt and 15N in platinum-am(m)ine antitumour drugs, provides information on the internalisation and subcellular localisation of both metal and ligands, and allows identification of ligand exchange.
Original language | English |
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Pages (from-to) | 6944-6946 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 49 |
Issue number | 62 |
DOIs | |
Publication status | Published - 11 Aug 2013 |
Externally published | Yes |