Natural products and their benefits on experimental hyperammonemia - a review

Subash Selvaraju, M. Mohamed Essa*, Mostafa I. Waly, Amanat Ali, Amani S. Al-Rawahi, Reshmi K. Vijayan, Gilles J. Guillemin, Subramanian Perumal, Tamilarasan Manivasagam, Annadurai Anandhan

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Natural products (phytochemicals), either as in whole food or as plant extracts,exhibit successful activity against numerous disease targets. Currently no efficient treatments are available that allow rapid and sustained decrease in blood ammonia levels. Natural plant phytochemicals have been reported to have some anti-hyperammonemic activity due to their antioxidant potential and removal of excess ammonia. This chapter reviews and discusses the medicinal properties and role of anti-hyperammonemic activity of natural plant phytochemicals such as Momordica charantia, Semecarpus anacardiumnut, Withania somnifera, Pongamia pinnata, Hibiscus sabdariffa, morin, and rutin. Natural products with antioxidant activity may be used to help in preventing a number of metabolic disorders and non-communicable diseases including hyperammonemia by reducing oxidative damage.

Original languageEnglish
Title of host publicationFood as medicine
EditorsM. Mohamed Essa, Mushtaq A. Memon
Place of PublicationNew York
PublisherNova Science Publishers
Number of pages21
ISBN (Electronic)9781624177828, 1624177824
ISBN (Print)9781624177477
Publication statusPublished - 2013
Externally publishedYes

Publication series

NameFood science and technology
PublisherNova Science Publishers


  • Momordica Charantia
  • Semecarpus anacardium nut
  • Withania somnifera
  • Pongamia pinnata
  • Hibiscus sabdariffa
  • morin
  • rutin
  • hyperammonemia


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