Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo

I. V. Zelepukin; M. P. Nikitin; A. V. Nechaev; A. V. Zvyagin; P. I. Nikitin; S. M. Deyev

doi:10.1109/LO.2016.7550011

Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo

I. V. Zelepukin, M. P. Nikitin, A. V. Nechaev, A. V. Zvyagin, P. I. Nikitin, S. M. Deyev

MQ Photonics Research Centre

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

1 Citation (Scopus)

Abstract

The methods of multimodal imaging are very attractive for a variety of applications in the field of life sciences. Here, we report synthesis of luminescent magnetic nanostructures based on upconversion nanophosphors and superparamagnetic iron oxide nanoparticles for their bimodal detection in vivo. Poly(lactic-co-glycolic acid) copolymer matrix was used for stabilization of nanoparticles in physiological pH and influence of reaction conditions on final size of nanoagents was investigated. The particles were studied by dynamic light scattering and transmission electron microscopy methods. The obtained particles are attractive for biomodal imaging inside small animals in vivo by the methods of optical tomography and magnetic particle quantification methods.

Original language	English
Title of host publication	Proceedings 2016 International Conference Laser Optics
Place of Publication	Piscataway, NJ
Publisher	Institute of Electrical and Electronics Engineers (IEEE)
Pages	S2-44
Number of pages	1
ISBN (Electronic)	9781467397353
DOIs	https://doi.org/10.1109/LO.2016.7550011
Publication status	Published - 23 Aug 2016
Event	2016 International Conference Laser Optics, LO 2016 - St. Petersburg, Russian Federation Duration: 27 Jun 2016 → 1 Jul 2016

Other

Other	2016 International Conference Laser Optics, LO 2016
Country/Territory	Russian Federation
City	St. Petersburg
Period	27/06/16 → 1/07/16

Keywords

bioimaging
luminescent tomography
magnetic detection
nanoparticles synthesis
spatial mapping

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10.1109/LO.2016.7550011

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@inproceedings{c773125cfb5845c280448e635babe3ad,

title = "Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo",

abstract = "The methods of multimodal imaging are very attractive for a variety of applications in the field of life sciences. Here, we report synthesis of luminescent magnetic nanostructures based on upconversion nanophosphors and superparamagnetic iron oxide nanoparticles for their bimodal detection in vivo. Poly(lactic-co-glycolic acid) copolymer matrix was used for stabilization of nanoparticles in physiological pH and influence of reaction conditions on final size of nanoagents was investigated. The particles were studied by dynamic light scattering and transmission electron microscopy methods. The obtained particles are attractive for biomodal imaging inside small animals in vivo by the methods of optical tomography and magnetic particle quantification methods.",

keywords = "bioimaging, luminescent tomography, magnetic detection, nanoparticles synthesis, spatial mapping",

author = "Zelepukin, {I. V.} and Nikitin, {M. P.} and Nechaev, {A. V.} and Zvyagin, {A. V.} and Nikitin, {P. I.} and Deyev, {S. M.}",

year = "2016",

month = aug,

day = "23",

doi = "10.1109/LO.2016.7550011",

language = "English",

pages = "S2--44",

booktitle = "Proceedings 2016 International Conference Laser Optics",

publisher = "Institute of Electrical and Electronics Engineers (IEEE)",

address = "United States",

note = "2016 International Conference Laser Optics, LO 2016 ; Conference date: 27-06-2016 Through 01-07-2016",

}

Zelepukin, IV, Nikitin, MP, Nechaev, AV, Zvyagin, AV, Nikitin, PI & Deyev, SM 2016, Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo. in Proceedings 2016 International Conference Laser Optics., 7550011, Institute of Electrical and Electronics Engineers (IEEE), Piscataway, NJ, pp. S2-44, 2016 International Conference Laser Optics, LO 2016, St. Petersburg, Russian Federation, 27/06/16. https://doi.org/10.1109/LO.2016.7550011

Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo. / Zelepukin, I. V.; Nikitin, M. P.; Nechaev, A. V. et al.
Proceedings 2016 International Conference Laser Optics. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE), 2016. p. S2-44 7550011.

Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review

TY - GEN

T1 - Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo

AU - Zelepukin, I. V.

AU - Nikitin, M. P.

AU - Nechaev, A. V.

AU - Zvyagin, A. V.

AU - Nikitin, P. I.

AU - Deyev, S. M.

PY - 2016/8/23

Y1 - 2016/8/23

N2 - The methods of multimodal imaging are very attractive for a variety of applications in the field of life sciences. Here, we report synthesis of luminescent magnetic nanostructures based on upconversion nanophosphors and superparamagnetic iron oxide nanoparticles for their bimodal detection in vivo. Poly(lactic-co-glycolic acid) copolymer matrix was used for stabilization of nanoparticles in physiological pH and influence of reaction conditions on final size of nanoagents was investigated. The particles were studied by dynamic light scattering and transmission electron microscopy methods. The obtained particles are attractive for biomodal imaging inside small animals in vivo by the methods of optical tomography and magnetic particle quantification methods.

AB - The methods of multimodal imaging are very attractive for a variety of applications in the field of life sciences. Here, we report synthesis of luminescent magnetic nanostructures based on upconversion nanophosphors and superparamagnetic iron oxide nanoparticles for their bimodal detection in vivo. Poly(lactic-co-glycolic acid) copolymer matrix was used for stabilization of nanoparticles in physiological pH and influence of reaction conditions on final size of nanoagents was investigated. The particles were studied by dynamic light scattering and transmission electron microscopy methods. The obtained particles are attractive for biomodal imaging inside small animals in vivo by the methods of optical tomography and magnetic particle quantification methods.

KW - bioimaging

KW - luminescent tomography

KW - magnetic detection

KW - nanoparticles synthesis

KW - spatial mapping

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DO - 10.1109/LO.2016.7550011

M3 - Conference proceeding contribution

AN - SCOPUS:84987927039

SP - S2-44

BT - Proceedings 2016 International Conference Laser Optics

PB - Institute of Electrical and Electronics Engineers (IEEE)

CY - Piscataway, NJ

T2 - 2016 International Conference Laser Optics, LO 2016

Y2 - 27 June 2016 through 1 July 2016

ER -

Near infrared luminescent-magnetic nanoparticles for bimodal imaging in vivo

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