Neural mechanisms of sensorimotor integration measured with fMRI

Tommy Ng Hock Beng, Theodore Milner

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

Abstract

It has been proposed that the brain combines prior knowledge of movement dynamics and sensory information from peripheral receptors, to obtain optimal force estimation. The present study investigated the neural mechanisms underlying this function. Subjects (N=20) trained in a torque-matching task to acquire knowledge of the dynamics and immediately after training, performed the same task under two conditions. Under pulse*c condition, torque pulse magnitude was always the same pulse*v condition, torque pulse magnitude changed pseudo-randomly according to a probability distribution (mean of 4.6 Nm ± 0.4). Hemodynamic responses corresponding to torque pulse compensation under the two conditions were contrasted. Results showed that the subjects compensated more accurately under pulse*c condition (4.20 ± 0.50 Nm), relative to pulse*v condition (4.00 ± 0.66 Nm). Pulse*v-pulse*c contrast revealed significant activation (P <0.001, uncorrected) of the right BA 6 and right BA 7. These results suggest that activity in right BA 6 was related to a computational process that was guided by the statistical properties of the perturbation magnitude, which led to the determination of an optimal response based on accumulation of prior knowledge. Activity of right BA 7 was related to retrieval of previously acquired neural representation from memory.
Original languageEnglish
Title of host publicationCombined abstracts of 2009 Australian Psychology Conferences
Editors Steven Roodenrys
Place of PublicationAustralia
PublisherThe Australian Psychological Society
Pages41-41
Number of pages1
ISBN (Print)9780909881405
Publication statusPublished - 2009
Externally publishedYes
Event36th Australasian Experimental Psychology Conference - Wollongong, Australia
Duration: 17 Apr 200919 Apr 2009

Conference

Conference36th Australasian Experimental Psychology Conference
CityWollongong, Australia
Period17/04/0919/04/09

Keywords

  • hemodynamic responses
  • BA 6
  • BA 7
  • neural representation

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