Neuro-ophthalmological manifestations of sarcoidosis

William B. Yates*, Peter J. McCluskey, Clare L. Fraser

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Neuro-sarcoidosis has important ophthalmic and neuro-ophthalmic manifestations. Sarcoidosis most commonly affects the uveal tract (iris, ciliary body, and choroid) however the optic nerve is commonly involved. Sarcoid related optic neuritis is an important differential diagnosis in optic neuritis especially in atypical presentations. The use of multimodal imaging techniques available in the ophthalmic setting can enable the detection of choroidal or optic nerve granulomas and aid the diagnosis. Efferent manifestations of neuro-sarcoidosis are broad and can range from isolated cranial neuropathies or multiple as well as pupil abnormalities. Currently to date there are no diagnostic framework to assist in the diagnosis of ophthalmic manifestations in neuro-sarcoidosis in the absence of a tissue biopsy.

Original languageEnglish
Article number577851
Pages (from-to)1-7
Number of pages7
JournalJournal of Neuroimmunology
Publication statusPublished - 15 Jun 2022
Externally publishedYes


  • Neuro-ophthalmic sarcoidosis
  • Ocular immunology
  • Sarcoidosis
  • Uveitis


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