Neuromuscular complications in HIV

effects of aging

Jessica Robinson-Papp*, Ik Lin Tan, David M. Simpson

*Corresponding author for this work

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

There has been speculation that chronic HIV infection is a condition of accelerated aging that may lead to early onset of disease in multiple organ systems. The neu-romuscular disorders of HIV, in particular distal symmetric polyneuropathy and myopathies, are also seen in the general population among older patients. As the HIV-infected population ages, there may be deleterious synergistic effects of age and chronic HIV infection on the brain, peripheral nerve, and muscle. In this review, we explore commonalities between the clinical features and putative mechanisms of neuromuscular disorders and HIV.

Original languageEnglish
Pages (from-to)331-338
Number of pages8
JournalJournal of NeuroVirology
Volume18
Issue number4
DOIs
Publication statusPublished - Aug 2012
Externally publishedYes

Keywords

  • Aging
  • AIDS
  • HIV
  • Myopathy
  • Neuromuscular
  • Neuropathy

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