Neuropsychological manifestations in a case of bilateral thalamic infarction

Steve Vucic*, T. Lye, R. A. Mackenzie

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Neuropsychological manifestation has been reported with lesions of the anterior and non-specific thalamic nuclei and mammilothalamic tract (MMT). These have been reported in the setting of arterial infarction and/or haemorrhage. Cerebral venous sinus thrombosis (CVT) is a rare cause of brain infarction. It occurs in the setting of oral contraceptive administration or pregnancy. Inherited thrombophilias are documented risk factors. The most frequent being heterozygous factor V Leiden mutation. We report a single case of bilateral thalamic infarction due to cerebral vein and sinus thrombosis. Clinically the case manifested with memory impairment and dysexecutive symptoms. Predisposing factor for venous thrombosis was a homozygous factor V Leiden mutation. The patient was treated with anticoagulation and made a good recovery.

Original languageEnglish
Pages (from-to)238-242
Number of pages5
JournalJournal of Clinical Neuroscience
Issue number2
Publication statusPublished - Mar 2003
Externally publishedYes


  • Cerebral vein thrombosis
  • Neuropsychological
  • Thalamic infarction


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