New integron-associated gene cassette encoding a trimethoprim-resistant DfrB-type dihydrofolate reductase

Renee S. Levings; Diane Lightfoot; Liam D H Elbourne; Steven P. Djordjevic; Ruth M. Hall

doi:10.1128/AAC.00449-06

New integron-associated gene cassette encoding a trimethoprim-resistant DfrB-type dihydrofolate reductase

Renee S. Levings, Diane Lightfoot, Liam D H Elbourne, Steven P. Djordjevic, Ruth M. Hall^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

A sixth gene cassette containing a dfrB-type gene, dfrB6, was found in a dfrB6-aadA1 cassette array in class 1 integrons. This array was isolated from several multiply antibiotic-resistant Salmonella enterica serovar Infantis strains that appear to be clonally related. The DfrB6 dihydrofolate reductase conferred resistance to trimethoprim.

Original language	English
Pages (from-to)	2863-2865
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	50
Issue number	8
DOIs	https://doi.org/10.1128/AAC.00449-06
Publication status	Published - Aug 2006
Externally published	Yes

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title = "New integron-associated gene cassette encoding a trimethoprim-resistant DfrB-type dihydrofolate reductase",

abstract = "A sixth gene cassette containing a dfrB-type gene, dfrB6, was found in a dfrB6-aadA1 cassette array in class 1 integrons. This array was isolated from several multiply antibiotic-resistant Salmonella enterica serovar Infantis strains that appear to be clonally related. The DfrB6 dihydrofolate reductase conferred resistance to trimethoprim.",

author = "Levings, {Renee S.} and Diane Lightfoot and Elbourne, {Liam D H} and Djordjevic, {Steven P.} and Hall, {Ruth M.}",

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AU - Lightfoot, Diane

AU - Elbourne, Liam D H

AU - Djordjevic, Steven P.

AU - Hall, Ruth M.

PY - 2006/8

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AB - A sixth gene cassette containing a dfrB-type gene, dfrB6, was found in a dfrB6-aadA1 cassette array in class 1 integrons. This array was isolated from several multiply antibiotic-resistant Salmonella enterica serovar Infantis strains that appear to be clonally related. The DfrB6 dihydrofolate reductase conferred resistance to trimethoprim.

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ER -

New integron-associated gene cassette encoding a trimethoprim-resistant DfrB-type dihydrofolate reductase

Abstract

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