New integron-associated gene cassette encoding a trimethoprim-resistant DfrB-type dihydrofolate reductase

Renee S. Levings, Diane Lightfoot, Liam D H Elbourne, Steven P. Djordjevic, Ruth M. Hall*

*Corresponding author for this work

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

A sixth gene cassette containing a dfrB-type gene, dfrB6, was found in a dfrB6-aadA1 cassette array in class 1 integrons. This array was isolated from several multiply antibiotic-resistant Salmonella enterica serovar Infantis strains that appear to be clonally related. The DfrB6 dihydrofolate reductase conferred resistance to trimethoprim.

Original languageEnglish
Pages (from-to)2863-2865
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume50
Issue number8
DOIs
Publication statusPublished - Aug 2006
Externally publishedYes

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