Night splinting does not increase ankle range of motion in people with Charcot-Marie-Tooth disease

a randomised, cross-over trial

Kathryn M. Refshauge, Jacqueline Raymond, Garth Nicholson, Paul A. van den Dolder

Research output: Contribution to journalArticle

37 Citations (Scopus)


Question: What is the effect of wearing splints at night to stretch the plantarflexors on dorsiflexion range of motion (ROM) in people with Charcot-Marie-Tooth disease? Design: Randomised, assessor-blinded, cross-over trial. Participants: 14 people (1 dropout) aged 7 to 30 years with Charcot-Marie-Tooth disease Type 1A and with ≤ 15 degrees dorsiflexion range of motion (ROM). Intervention: A splint holding the ankle in maximum dorsiflexion was worn nightly on one leg for 6 weeks followed by the opposite leg for the subsequent 6 weeks. Outcome measures: The primary outcome was dorsiflexion RQM; secondary outcomes were eversion ROM, and dorsiflexion, eversion, and inversion strength, measured before and after splinting, and three months later. Results: There was no significant difference between the experimental and the control intervention in terms of ROM or strength. Wearing the splint at night increased dorsiflexion ROM by 1 degree (95% CI -3 to 4; p = 0.72) and eversion ROM by 1 degree (95% CI -1 to 3; p = 0.28) compared to not wearing the splint. Wearing the splint increased dorsiflexion strength by 41 N (95% CI -53 to 135; p = 0.38), reduced eversion strength by 6 N (95% CI -112 to 101; p = 0.92) and reduced inversion strength by 8 N (95% CI -110 to 95; p = 0.88) compared to not wearing the splint. Conclusion: Wearing night splints does not increase ankle ROM or strength in people with Charcot-Marie-Tooth disease Type 1A.

Original languageEnglish
Pages (from-to)193-199
Number of pages7
JournalAustralian Journal of Physiotherapy
Issue number3
Publication statusPublished - 2006
Externally publishedYes



  • Charcot-Marie-Tooth disease
  • Peripheral neuropathy
  • Pes Cavus
  • Physical therapy modalities
  • Stretching

Cite this