Nitration of pre-assembled Troger's base analogs

M. Delower H. Bhuiyan, Andrew C. Try

    Research output: Contribution to journalMeeting abstract


    The presence of a nitro functional group on an aromatic ring provides a valuable entry point for the introduction of other functionalities such as amine, diazo, hydroxyl, nitrite etc. In our present study we have used urea nitrate and potassium nitrate to introduce nitro groups onto several Tröger's base compounds, post-assembly of the skeleton. We have also examined the regiochemistry of the reactions in the presence of different nitrating agents and the effect of R groups with differing activating effects These reactions constitute the first examples of direct introduction of the nitro functional group on pre-assembled Tröger’s base analogs.
    Original languageEnglish
    Pages (from-to)181
    Number of pages1
    JournalJournal of the Mexican Chemical Society : IUPAC ICOS-16 conference program and abstract of papers
    Publication statusPublished - 2006
    EventInternational Conference on Organic Synthesis (16th : 2006) - Merida, Mexico
    Duration: 11 Jun 200615 Jun 2006


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