Nitration of pre-assembled Troger's base analogs

M. Delower H. Bhuiyan, Andrew C. Try

Research output: Contribution to journalMeeting abstract


The presence of a nitro functional group on an aromatic ring provides a valuable entry point for the introduction of other functionalities such as amine, diazo, hydroxyl, nitrite etc. In our present study we have used urea nitrate and potassium nitrate to introduce nitro groups onto several Tröger's base compounds, post-assembly of the skeleton. We have also examined the regiochemistry of the reactions in the presence of different nitrating agents and the effect of R groups with differing activating effects These reactions constitute the first examples of direct introduction of the nitro functional group on pre-assembled Tröger’s base analogs.
Original languageEnglish
Pages (from-to)181
Number of pages1
JournalJournal of the Mexican Chemical Society : IUPAC ICOS-16 conference program and abstract of papers
Publication statusPublished - 2006
EventInternational Conference on Organic Synthesis (16th : 2006) - Merida, Mexico
Duration: 11 Jun 200615 Jun 2006

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