Nitrogenous bisabolene sesquiterpenes from marine invertebrates

Nanda K. Gulavita, E. Dilip De Silva, Mark R. Hagadone, Peter Karuso, Paul J. Scheuer*, Gregory D. Van Duyne, Jon Clardy

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

74 Citations (Scopus)


Three bisabolene sesquiterpenes, an amine hydrochloride (8), an isocyanate (9), and an isocyano derivative (16), were isolated from a sponge, Ciocalypta sp. The structure of the isocyanate was proven by X-ray diffraction of its (p-bromobenzyl)urea derivative. From a nudibranch, Phyllidia sp., from Sri Lanka, we isolated the previously unreported 3-isocyanotheonellin (11).

Original languageEnglish
Pages (from-to)5136-5139
Number of pages4
JournalJournal of Organic Chemistry
Issue number26
Publication statusPublished - 1986
Externally publishedYes


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