Normal perfusion pressure breakthrough complicating surgery for the vein of Galen malformation: report of three cases

Michael K. Morgan, Ian H. Johnston, Thoralf M. Sundt

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Three cases are described of infants who developed malignant brain swelling (and in one case hemorrhage) after surgery for vein of Galen malformations. The cause for the brain swelling was felt to be due to hyperperfusion, or the “normal perfusion pressure breakthrough” syndrome. Although well-described for cerebral parenchymal arteriovenous malformations, cases of this complication occurring in vein of Galen malformations have not previously been reported. It is concluded from these cases that infants with large arteriovenous shunts, as attested by cardiac failure and cerebral atrophy, have an increased risk of developing this complication.
Original languageEnglish
Pages (from-to)406-410
Number of pages5
JournalNeurosurgery
Volume24
Issue number3
DOIs
Publication statusPublished - Mar 1989
Externally publishedYes

Keywords

  • vein of Galen
  • aneurysm
  • circulation
  • cerebrum
  • hyperemia
  • complication

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