Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy

Yichen Ding, Yu Zhang, Tong Peng, Yiqing Lu, Dayong Jin, Qiushi Ren, Yuying Liu, Jingyan Han*, Peng Xi

*Corresponding author for this work

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contrast images of leukocytes were obtained. The extended detection capability facilitated both the automatic in vivo cell counting and the accurate measurement of the rolling velocity of leukocytes. Statistical analysis of the different treatment groups suggested that the distinction between I/R and sham groups with time lapse is significant.

Original languageEnglish
Article number1762
Pages (from-to)1-6
Number of pages6
JournalScientific Reports
Volume3
DOIs
Publication statusPublished - 2013

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