Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy

Yichen Ding; Yu Zhang; Tong Peng; Yiqing Lu; Dayong Jin; Qiushi Ren; Yuying Liu; Jingyan Han; Peng Xi

doi:10.1038/srep01762

Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy

Yichen Ding, Yu Zhang, Tong Peng, Yiqing Lu, Dayong Jin, Qiushi Ren, Yuying Liu, Jingyan Han^*, Peng Xi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contrast images of leukocytes were obtained. The extended detection capability facilitated both the automatic in vivo cell counting and the accurate measurement of the rolling velocity of leukocytes. Statistical analysis of the different treatment groups suggested that the distinction between I/R and sham groups with time lapse is significant.

Original language	English
Article number	1762
Pages (from-to)	1-6
Number of pages	6
Journal	Scientific Reports
Volume	3
DOIs	https://doi.org/10.1038/srep01762
Publication status	Published - 2013

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10.1038/srep01762

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abstract = "Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contrast images of leukocytes were obtained. The extended detection capability facilitated both the automatic in vivo cell counting and the accurate measurement of the rolling velocity of leukocytes. Statistical analysis of the different treatment groups suggested that the distinction between I/R and sham groups with time lapse is significant.",

author = "Yichen Ding and Yu Zhang and Tong Peng and Yiqing Lu and Dayong Jin and Qiushi Ren and Yuying Liu and Jingyan Han and Peng Xi",

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T1 - Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy

AU - Ding, Yichen

AU - Zhang, Yu

AU - Peng, Tong

AU - Lu, Yiqing

AU - Jin, Dayong

AU - Ren, Qiushi

AU - Liu, Yuying

AU - Han, Jingyan

AU - Xi, Peng

PY - 2013

Y1 - 2013

N2 - Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contrast images of leukocytes were obtained. The extended detection capability facilitated both the automatic in vivo cell counting and the accurate measurement of the rolling velocity of leukocytes. Statistical analysis of the different treatment groups suggested that the distinction between I/R and sham groups with time lapse is significant.

AB - Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contrast images of leukocytes were obtained. The extended detection capability facilitated both the automatic in vivo cell counting and the accurate measurement of the rolling velocity of leukocytes. Statistical analysis of the different treatment groups suggested that the distinction between I/R and sham groups with time lapse is significant.

UR - https://www.scopus.com/pages/publications/84878634420

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DO - 10.1038/srep01762

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VL - 3

SP - 1

EP - 6

JO - Scientific Reports

JF - Scientific Reports

M1 - 1762

ER -

Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy

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