TY - JOUR
T1 - Opportunities for electroceuticals in epilepsy
AU - Kavehei, Omid
AU - Hamilton, Tara Julia
AU - Truong, Nhan Duy
AU - Nikpour, Armin
PY - 2019/10
Y1 - 2019/10
N2 - Epilepsy is a neurological disorder that affects ∼1% of the world population. Nearly 30% of epilepsy patients suffer from pharmacoresistant epilepsy that cannot be treated with antiepileptic drugs. Depending on seizure type, a diverse range of therapies are available, including surgery, vagus nerve stimulation, and deep brain stimulation. We review the sensing and stimulation technologies most used in neurological disorders, and provide a vision of minimally invasive electroceuticals to enable accurate forecasting of epileptic seizures and therapy. The use of such systems could potentially help patients to prevent injuries and, in combination with an intervention mechanism, could provide a method of suppressing seizures in epileptic patients.
AB - Epilepsy is a neurological disorder that affects ∼1% of the world population. Nearly 30% of epilepsy patients suffer from pharmacoresistant epilepsy that cannot be treated with antiepileptic drugs. Depending on seizure type, a diverse range of therapies are available, including surgery, vagus nerve stimulation, and deep brain stimulation. We review the sensing and stimulation technologies most used in neurological disorders, and provide a vision of minimally invasive electroceuticals to enable accurate forecasting of epileptic seizures and therapy. The use of such systems could potentially help patients to prevent injuries and, in combination with an intervention mechanism, could provide a method of suppressing seizures in epileptic patients.
UR - http://www.scopus.com/inward/record.url?scp=85071720489&partnerID=8YFLogxK
U2 - 10.1016/j.tips.2019.08.001
DO - 10.1016/j.tips.2019.08.001
M3 - Comment/opinion
C2 - 31495453
AN - SCOPUS:85071720489
SN - 0165-6147
VL - 40
SP - 735
EP - 746
JO - Trends in Pharmacological Sciences
JF - Trends in Pharmacological Sciences
IS - 10
ER -